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07-363

Sigma-Aldrich

Anti-AMPK α2 Antibody

Upstate®, from rabbit

Synonyme(s) :

AMP-Activated Protein Kinase, AMPK

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human, rat

Fabricant/nom de marque

Upstate®

Technique(s)

western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

NM_006252

Numéro d'accès UniProt

P54646

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... PRKAA2(5563)

Spécificité

Recognizes AMP-Activated Protein Kinase alpha2 (AMPKα2).

Immunogène

peptide corresponding to amino acids 353-367 (C-DDSAMHIPPGLKPHP) of human AMP-Activated Protein Kinase alpha2 (AMPKalpha2) catalytic subunit

Application

Detect AMPK α2 using this Anti-AMPK α2 Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Qualité

routinely evaluated by immunoblot in a rat liver preparation

Description de la cible

~63 kDa

Forme physique

Format: Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Protein A purified

Stockage et stabilité

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Remarque sur l'analyse

Control
Rat liver preparation

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Data in support of 5'AMP-activated protein kinase alpha regulates stress granule biogenesis.
Mahboubi, H; Barise, R; Stochaj, U
Data in Brief null
B J Michell et al.
The Journal of biological chemistry, 271(45), 28445-28450 (1996-11-08)
The 5'-AMP-activated protein kinase (AMPK) mediates several cellular responses to metabolic stress. Rat liver contains at least two isoforms of this enzyme, either alpha1 or alpha2 catalytic subunits together with beta and gamma noncatalytic subunits in a trimeric complex. The
Miki Tadaishi et al.
American journal of physiology. Endocrinology and metabolism, 300(2), E341-E349 (2010-11-26)
There are three isoforms of peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) mRNA, which promotes mitochondrial biogenesis in skeletal muscles. Compared with PGC-1α-a mRNA, PGC-1α-b or PGC-1α-c mRNA is transcribed by a different exon 1 of the PGC-1α gene. In this
TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.
An, D; Toyoda, T; Taylor, EB; Yu, H; Fujii, N; Hirshman, MF; Goodyear, LJ
Diabetes null
TBC 11251. IPI 1040.
Drugs in R&D, 2(1), 38-39 (1999-12-28)
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