07-1223

Anti-Protein Phosphatase 2 C α/β Antibody

from rabbit

• Synonyme(s) : Protein phosphatase 2C, Pyruvate dehydrogenase, Pyruvate dehydrogenase phosphatase, catalytic subunit 1, Lipoamide-phosphatase 1, mitochondrial precursor, Protein phosphatase 2C, magnesium-dependent, catalytic subunit, Pyruvate dehydrogenase (Lipoamide)
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Espèces réactives: bovine, human, rat
• Réactivité de l'espèce (prédite par homologie): mouse
• Technique(s): western blot: suitable
• Numéro d'accès UniProt: Q9P0J1
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... PDP1(54704)

Description

Description générale

PP-2 C α/β is heterodimer located in the mitochondrial matrix. Within the pyruvate dehydrogenase complex, PP-2 C α/β serves to catalyze the dephosphorylation and concomitant reactivation of the E1 component’s alpha subunit. Mutations occurring in the PDP1 gene are the cause of a disease known as pyruvate dehydrogenase deficiency (PDP deficiency), which leads to neurological dysfunction from lactic acidosis.

Spécificité

Recognizes the alpha/beta regulatory subunit isotype of protein phosphatase 2C (PP2C). PP 2C alpha/beta polyclonal antibody binds a 44-46 kDa protein.

Immunogène

Purified peptide conjugated to KLH.

Application

Detect Protein Phosphatase 2 C α/β using this Anti-Protein Phosphatase 2 C α/β Antibody validated for use in WB.

Research Category
Signaling

Research Sub Category
Kinases & Phosphatases

Qualité

Evaluated by Western Blot in L6 cell lysates.
Western Blot Analysis: 1:500 dilution of this lot detected PP-2 C ALPHA/BETA on 10 ug of L6 lysates.

Description de la cible

Approx. 46 kDa

Liaison

Replaces: AB4090

Forme physique

Format: Purified

Protein Purified

Purified immunoglobulin in phosphate buffered saline with 0.08% sodium azide.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Remarque sur l'analyse

Control
L6 Cell Lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable