M-152

Mitragynine solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill): C₂₃H₃₀N₂O₄
• Numéro CAS: 4098-40-2
• Poids moléculaire : 398.50
• Numéro CE : 200-659-6
• Numéro MDL: MFCD09838906
• Code UNSPSC : 41116107
• ID de substance PubChem : 329817883
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 100 μg/mL in methanol
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): forensics and toxicology
• Format: single component solution
• Température de stockage: −20°C
• Chaîne SMILES: O=C(OC)/C([C@H]1C[C@@](N(C[C@H]1CC)CC2)([H])C3=C2C(C(OC)=CC=C4)=C4N3)=C/OC
• InChI: 1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1
• Clé InChI: LELBFTMXCIIKKX-QVRQZEMUSA-N

Description

Description générale

Mitragynine, commonly known as Kratom, is the most abundant alkaloid in the plant Mitragynine speciosa. Sold over the internet as herbal plant extracts, Kratom is noted for its psychoactive, stimulant, and sedative effects depending on the dosage level. According to DEA′s Drugs and Chemicals of Concern page, mitragynine use can lead to addiction with adverse effects ranging from anorexia and weight loss to hallucinations and delusion.

Application

• Pharmacokinetic Interaction of Kratom and Cannabidiol: A study analyzed the pharmacokinetic interactions between mitragynine and cannabidiol in male rats, providing critical insights for co-administration of these compounds (Berthold et al., 2024).



• Enhancement of Low-Dose Doxorubicin Cytotoxicity by Kratom Extracts: Research investigated whether kratom extracts enhance the cytotoxic effects of low-dose doxorubicin against lung cancer cells, suggesting a potential use of mitragynine in cancer therapy (Bayu et al., 2024).



• Extraction and Detection of Mitragynine: A technique using high-performance liquid chromatography for the extraction and detection of mitragynine from Kratom leaves was developed, enhancing the accuracy and efficiency of mitragynine isolation for research purposes (Ng and Ha, 2024).



• Amelioration of Mitragynine Withdrawal Symptoms: A study explored the potential of an epigenetic mechanism to ameliorate withdrawal behavior and cognitive impairments caused by mitragynine, contributing to better management strategies for opioid withdrawal symptoms (Yunusa et al., 2024).



• Imaging Mass Spectrometry Analysis of Mitragynine: Research utilized MALDI imaging mass spectrometry to study the distribution of Mitragyna speciosa alkaloids, including mitragynine, in dosed rat brain tissue, advancing the understanding of its biochemical behavior (Liang et al., 2024).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes,Central nervous system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup