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G-001

Supelco

GHB sodium salt solution

1.0 mg/mL in methanol (as salt), ampule of 1 mL, certified reference material, Cerilliant®

Synonyme(s) :

4-Hydroxybutyric acid sodium salt solution

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About This Item

Formule empirique (notation de Hill):
C4H7NaO3
Numéro CAS:
502-85-2
Poids moléculaire :
126.09
Numéro CE :
200-659-6
Numéro MDL:
MFCD00004402
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

Concentration

1.0 mg/mL in methanol (as salt)

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

forensics and toxicology

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

OCCCC([O-])=O.[Na+]

InChI

1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)/p-1

Clé InChI

SJZRECIVHVDYJC-UHFFFAOYSA-M

Catégories apparentées

Description générale

GHB, or γ-hydroxybutyrate, is a central nervous system depressant sold under the brand name Xyrem® and used medically to treat narcolepsy, excessive daytime sleepiness and in rare circumstances, alcoholism. GHB is also used recreationally as an intoxicant and date rape drug. Its many street names include “GBH”, “Liquid X”, “G”, “Juice”, and “Mils”.

Application


  • GHB sodium salt in sleep disorder research: A study on nocturnal sodium oxybate, a form of GHB sodium salt, revealed an increase in the anterior cingulate cortex magnetic resonance glutamate signal upon awakening, suggesting its potential application in modulating brain function in sleep research (Dornbierer et al., 2023).

  • Investigation of GHB Na+ in alcohol-addiction treatment: Research focusing on the effect of the sodium salt of gamma-hydroxybutyrate (GHB) for alcohol-addiction treatment, it is effective in maintaining abstinence, with less craving for alcohol and lower rates of relapse (Frisoni et al., 2023).

  • Gamma-hydroxybutyrate sodium for in vitro biochemical assays: A detailed study on the pharmacokinetics and metabolism of gamma-hydroxybutyrate (GHB) in rats perturbed by alcohol, offers a model for in vitro studies examining GHB′s biochemical behavior and interaction with alcohol (Kim et al., 2023).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Xyrem is a registered trademark of JPI Commercial, LLC

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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2-Hydroxybutyric acid sodium salt 97%

Sigma-Aldrich

220116

2-Hydroxybutyric acid sodium salt

β-Butyrolactone 98%

Sigma-Aldrich

219126

β-Butyrolactone

(±)-3-Hydroxybutyrate de sodium ≥99.0% (NT)

Sigma-Aldrich

54965

(±)-3-Hydroxybutyrate de sodium

Anna Krajewska et al.
Przeglad lekarski, 69(8), 544-547 (2012-12-19)
Gammabutyrolactone is included in the solvent such as wheel cleaners, pesticides, cosmetics, drugs. After ingestion GBL is converted to gamma-hydroxybutyrate. Both substances are classified as so called "club drugs" and their action is characterized by euphoria, sedation, and induction of
The limits of free speech.
Nature, 492(7429), 311-311 (2013-01-03)
R W Freudenmann et al.
Fortschritte der Neurologie-Psychiatrie, 81(2), 88-94 (2013-02-16)
In emergency medicine and anesthaesiology liquid ecstasy (LE), the street name for GHB, GBL or 1,4-B, has become infamous for causing severe intoxications and withdrawal. In general psychiatry, however, it is little known. Therefore, we set out to gather data
Robert Neijzen et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(5), 801-803 (2012-09-29)
Intoxications with gamma-hydroxybutyrate (GHB) are occurring more frequently. Patients are primarily treated symptomatically. The use of activated charcoal (AC) has been suggested in several guidelines and in literature, although the clinical value of AC in GHB intoxication is a matter
γ-Hydroxybutyrate toxicity mimicking basilar artery stroke.
N S N Graham et al.
British journal of hospital medicine (London, England : 2005), 73(7), 412-413 (2012-08-10)
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