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841138P

Avanti

Egg PG

Avanti Research™ - A Croda Brand

Synonyme(s) :

1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-sn-1-glycerol sodium salt, L-α-phosphatidylglycerol (Egg, Chicken) (sodium salt)

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About This Item

Numéro CAS:
383907-64-0
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 2 × 100 mg (841138P-200mg)
pkg of 5 × 100 mg (841138P-500mg)
pkg of 1 × 25 mg (841138P-25mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand

Type de lipide

phosphoglycerides

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

Description générale

Phosphatidylglycerol (PG) is one of the major phospholipids in food and biological tissues. PG, structurally has two acyl chains esterified to a glycerol, which in turn is bonded to a headgroup structure that has phosphate and carries negative charge. PG is abundant in bacterial membranes and present in lower amounts in mammalian membranes. It is abundant in lung surfactant. PG is synthesized from cytidine phosphate-diacylglycerol (CDP-DAG).

Application

Egg PG has been used as anionic phospholipid substrate in serial protein misfolding cyclic amplification (sPMCA) reaction. It is also suitable for use in the preparation of large unilamellar vesicles (LUVs) and as a standard for liquid chromatography-mass spectrometric analysis (LC-MS).

Actions biochimiques/physiologiques

Phosphatidylglycerol (PG) is an indicator of fetal lung maturity. It is a precursor for cardiolipin in animals. In plants, PG is present in thylakoid membranes and plays a central role in photosynthesis.

Conditionnement

5 mL Clear Glass Sealed Ampule (841138P-200mg)
5 mL Clear Glass Sealed Ampule (841138P-25mg)
5 mL Clear Glass Sealed Ampule (841138P-500mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Certificats d'analyse (COA)

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Phosphatidylglycerol in amniotic fluid: comparison of an ?ultrasensitive? immunologic assay with TLC and enzymatic assay
Eisenbrey AB, et al.
American Journal of Bioscience, 91(3), 293-297 (1989)
Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids
Deleault NR, et al.
Proceedings of the National Academy of Sciences, 109(22), 8546-8551 (2012)
The
An Introduction to Biological Membranes: Composition, Structure and Function, 91(3) (2016)
The
The Membranes of Cells, 911(3) (2016)
Célia Jacoberger-Foissac et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 152, 348-357 (2020-06-02)
Liposomes are powerful tools for the optimization of peptides and adjuvant composition in cancer vaccines. Here, we take advantage of a liposomal platform versatility to develop three vaccine candidates associating a peptide from HA influenza virus protein as CD4 epitope
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