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P1659

Sigma-Aldrich

Pelargonidin chloride

Synonyme(s) :

3,4′,5,7-Tetrahydroxyflavylium chloride, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-1-benzopyrylium chloride, Pelargonidol chloride

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About This Item

Formule empirique (notation de Hill):
C15H11ClO5
Numéro CAS:
134-04-3
Poids moléculaire :
306.70
Numéro Beilstein :
3922945
Numéro CE :
205-127-7
Numéro MDL:
MFCD00017589
Code UNSPSC :
12352100
ID de substance PubChem :
57654503
Nomenclature NACRES :
NA.22

Forme

powder

Température de stockage

2-8°C

Chaîne SMILES 

[Cl-].Oc1ccc(cc1)-c2[o+]c3cc(O)cc(O)c3cc2O

InChI

1S/C15H10O5.ClH/c16-9-3-1-8(2-4-9)15-13(19)7-11-12(18)5-10(17)6-14(11)20-15;/h1-7H,(H3-,16,17,18,19);1H

Clé InChI

YPVZJXMTXCOTJN-UHFFFAOYSA-N

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Application

Involved in pharmacological studies investigating the use of flavonoids as inhibitors of CD38

Antioxidant and anthocyanidin:
  • Found in various natural sources evaluated for inhibitory effects on colon and liver cancer cells
  • Used as hyroperoxide and hydrogen peroxide scavenging substance
  • Used to study relationship between structure, antioxidant capacity and redox potentials
  • Studied to determine the mechanism of radical-scavenging

Actions biochimiques/physiologiques

Antioxidant and anthocyanidin.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Petunidin 3-glucoside chloride phyproof® Reference Substance

PHL89755

Petunidin 3-glucoside chloride

Malvidin chloride phyproof® Reference Substance

PHL80083

Malvidin chloride

Callistephin chloride ≥95.0% (HPLC)

Sigma-Aldrich

53489

Callistephin chloride

Chan Ho Jang et al.
Nutrients, 11(4) (2019-04-17)
Certain antioxidative flavonoids are known to activate nuclear factor E2-related factor 2 (Nrf2), a transcription factor that regulates cellular antioxidants and detoxifying response and is reportedly highly activated in many types of cancers. Few studies on the potential undesired effects
Catherine Felgines et al.
The Journal of nutrition, 133(5), 1296-1301 (2003-05-06)
Anthocyanins are phenolic compounds widely distributed in fruits and vegetables. Their consumption has been shown to prevent some chronic diseases. Anthocyanin metabolism, however, is still not fully understood. The aim of this work was to evaluate the bioavailability of anthocyanins
Hamid Sohanaki et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 83, 85-91 (2016-10-25)
Alzheimer's disease (AD) is a multifactorial disorder with devastating outcomes and few mostly palliative available therapeutic strategies. Pelargonidin (Pel), an anthocyanin compound, is an estrogen receptor agonist with lower side effects versus estrogen. This study examined neuroprotective effect of Pel
Sridaran Dhivya et al.
Integrative cancer therapies, 15(4), 525-534 (2016-05-06)
Hypothesis Anthocyanins possess well-known biological effects and suppress DNA damage induced by therapeutic topoisomerase poisons. Our study focusses on the modulatory effects of anthocyanidins-malvidin (MAL) and pelargonidin (PEL)-on topoisomerase II poison mitoxantrone (MXT)-induced cytotoxicity and genotoxicity in in vitro and
Gabor Kottra et al.
The Journal of pharmacology and experimental therapeutics, 322(2), 829-835 (2007-05-15)
There is controversy as to whether intestinal absorption of glycosylated flavonoids, and particularly quercetin glycosides, involves their uptake in intact form via the human sodium-coupled glucose transporter hSGLT1. We here describe studies using Xenopus oocytes that express hSGLT1 and the
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