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913960

Sigma-Aldrich

Conjugated Polymer Nanoparticles incorporating iron oxide

fluorescence λem 420 nm, 100 μg/mL in H2O

Synonyme(s) :

Conjugated polymer nanoparticles, Fluorescent magnetic nanoparticles, Fluorescent nanoparticles, Magneto-conjugated polymer nanoparticles

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About This Item

Code UNSPSC :
12352303
Nomenclature NACRES :
NA.23

Forme

nanoparticles

Niveau de qualité

100

Concentration

100 μg/mL in H2O

Fluorescence

λem 420 nm

Température de stockage

2-8°C

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Application

Iron oxide containing conjugated polymer nanoparticles are water-soluble nanoparticles compromising of light-emitting polymer and iron oxide. The presence of iron oxide in core makes these fluorescent nanoparticles distinctly different than conventional dyes as it allows their manipulation with a magnetic field. These nanoparticles possess a ′core-shell′ structure where light-emitting polymer and iron oxide are encapsulated in biocompatible surfactant.
The ′core-shell′ structure consisting of polymer and iron oxide in the core and the biocompatible surfactant in the surrounding shell allows easy covalently bonding of these nanoparticles with biomolecules such streptavidin, antibodies, proteins, nucleic acids, etc and make them suitable for the following applications:
  • Fluorescence Microscopy (high content screening, live cell tracking and 3-D cell imaging)
  • Immunohistochemistry and Immunocytochemistry
  • Flow Cytometry
  • Rapid Diagnostic Tests (RDTs)
  • Tissue Imaging
  • 2-Photon Imaging
  • NIR Imaging

Stockage et stabilité

The robustness of CPNs enables them to be used under high intensity illumination and in extreme experimental conditions if required, while their 24-month shelf-life permits convenient storage at ambient temperatures

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

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Consulter la Bibliothèque de documents

General synthesis of high-performing magneto-conjugated polymer core?shell nanoparticles for multifunctional theranostics.
Yan H, et al.
Nano Research, 10, 704-704 (2017)
Philip Howes et al.
Journal of the American Chemical Society, 132(28), 9833-9842 (2010-06-25)
Hybrid nanoparticles which incorporate multiple functionalities, such as fluorescence and magnetism, can exhibit enhanced efficiency and versatility by performing several tasks in parallel. In this study, magnetic-fluorescent semiconductor polymer nanospheres (MF-SPNs) have been synthesized by encapsulation of hydrophobic conjugated polymers

Articles

Applications of Iron Oxide Incorporated Conjugated Polymer Nanoparticles

CPNs offer sensitivity and stability, aiding various assays; may enable rapid diagnostic tests for healthcare needs.

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