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81381

Sigma-Aldrich

Alcool polyvinylique

Mw ~31,000

Synonyme(s) :

Poly(vinyl alcohol)

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About This Item

Formule linéaire :
[-CH2CHOH-]n
Numéro CAS:
9002-89-5
Numéro MDL:
MFCD00081922
Code UNSPSC :
12352104
Nomenclature NACRES :
NA.23

Forme

crystals

Poids mol.

Mw ~31,000

Ampleur du marquage

86.7-88.7 mol% hydrolysis
~630 polymerization

Résidus de calcination

≤0.5%

Viscosité

3.5-4.5 mPa.s, 4 % in H2O(20 °C)

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

Clé InChI

IMROMDMJAWUWLK-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Mowiol® is a water soluble hydrocolloid mucoadhesive based on poly (vinyl alcohol). Mowiol® at pH 8.5 has a couple of advantages over other mounting media:
  • its a liquid when the sample is mounted and solidifies after several hours, forming a permanent bond between the coverslip and slide
  • fluorescence is stable when held in dark and at 4oC.

Application

Mowiol® is used as an embedding medium for preserving stained cell dishes in the study of siRNA array production of HeLa cells. Mowiol® is also reported to be used as a mounting medium in:
  • design of TSAR and its applications
  • detection of the secreted and cytoplasmic fractions of IpaB, IpaC and IpaD by lysozyme permeabilization
  • fluorescence recovery after photobleaching (FRAP).

Mowiol® may be used as a coating for sensors based on piezoelectric quartz crystals. Another probable use of Mowiol® is during the study of super fluorescence imaging of biocompatible carbon dots.

Informations légales

Mowiol is a registered trademark of Kuraray Europe GmbH

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

No data available

Point d'éclair (°C)

No data available

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Xiaofang Li et al.
Scientific reports, 7(1), 16495-16495 (2017-12-01)
Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer patients is an unsolved issue. Here, we systematically analyzed the aberrant expression patterns of cervical cancer using RNA-Seq data from The Cancer Genome Atlas (TCGA). We incorporated gene profiling
Super-resolution fluorescence imaging of biocompatible carbon dots.
Lemenager G, et al.
Nanoscale, 6, 8614-8623 (2014)
Avgi Tsolou et al.
Life sciences, 232, 116562-116562 (2019-06-16)
Lung cancer is one of the main causes of cancer-related deaths worldwide and radiotherapy is a major treatment of choice. However, radioresistance is a main reason for radiotherapy failure or tumor relapse. Here, we investigated possible mechanisms associated with cancer
Cedric S Tremblay et al.
Nature communications, 9(1), 3535-3535 (2018-09-01)
Pre-leukemic stem cells (pre-LSCs) give rise to leukemic stem cells through acquisition of additional gene mutations and are an important source of relapse following chemotherapy. We postulated that cell-cycle kinetics of pre-LSCs may be an important determinant of clonal evolution
A Kondratskyi et al.
Cell death & disease, 5, e1193-e1193 (2014-04-26)
The growing number of studies suggested that inhibition of autophagy enhances the efficacy of Akt kinase inhibitors in cancer therapy. Here, we provide evidence that ML-9, a widely used inhibitor of Akt kinase, myosin light-chain kinase (MLCK) and stromal interaction
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