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693839

Sigma-Aldrich

6-Phosphonohexanoic acid

97%

Synonyme(s) :

PHA

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About This Item

Formule empirique (notation de Hill):
C6H13O5P
Numéro CAS:
5662-75-9
Poids moléculaire :
196.14
Numéro MDL:
MFCD10000902
Code UNSPSC :
12352103
ID de substance PubChem :
329761625
Nomenclature NACRES :
NA.23

Pureté

97%

Forme

solid

Pf

98-104 °C

Chaîne SMILES 

OC(=O)CCCCCP(O)(O)=O

InChI

1S/C6H13O5P/c7-6(8)4-2-1-3-5-12(9,10)11/h1-5H2,(H,7,8)(H2,9,10,11)

Clé InChI

SYFTUNQVCGSBOV-UHFFFAOYSA-N

Catégories apparentées

Description générale

6-Phosphonohexanoic acid (PHA) is an alkylphosphonic acid that forms a self-assembled monolayer (SAM) on a variety of surfaces. It has carboxylic groups that facilitate the grafting of the surface atoms while the phosphonic groups allow the surface modification of the substrate material.

Application

PHA can be used in the surface functionalization of phynox material which can further be utilized in the biomedical applications such as surgical implant and stents. It can also be used in dispersing manganese dioxide (MnO2)-MWCNT for the formation of electrodes for supercapacitors. It may also be coated on indium tin oxide (ITO) as an alternative to silane based SAMs for the fabrication of organic electronic devices such as organic solar cells (OSCs).

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Surface modification of alumina-coated silica nanoparticles in aqueous sols with phosphonic acids and impact on nanoparticle interactions
Pauly CS, et al.
Physical Chemistry Chemical Physics, 17(29), 19173-19182 (2015)
Mariana E Mendes et al.
International journal of radiation biology, 95(8), 1058-1071 (2019-04-23)
Purpose: The goal was to compare the micronucleus (MN) and dicentric plus ring chromosomes (D + R) assays for dose assessment in cases of partial body irradiations (PBI). Materials and methods: We constructed calibration curves for each assay at doses ranging from
Shulian Tan et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(41), 10954-10959 (2017-09-07)
There is an urgent and unmet need for humanized in vivo models of type 1 diabetes to study immunopathogenesis and immunotherapy, and in particular antigen-specific therapy. Transfer of patient blood lymphocytes to immunodeficient mice is associated with xenogeneic graft-versus-host reactivity
Elena Herrera-Carrillo et al.
PloS one, 12(5), e0177935-e0177935 (2017-05-26)
Allogeneic transplantation of blood stem cells from a CCR5-Δ32 homozygous donor to an HIV-infected individual, the "Berlin patient", led to a cure. Since then there has been a search for approaches that mimic this intervention in a gene therapy setting.
Channarena Chuon et al.
Scientific reports, 9(1), 12186-12186 (2019-08-23)
Approximately 75% of hepatocellular carcinomas (HCC) occur in Asia; core promoter mutations are associated with HCC in HBV genotype C, the dominant genotype in Cambodia. We analyzed these mutations in Cambodian residents and compared them with HBV full genomes registered
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