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523801

Sigma-Aldrich

N,N-Dimethylphenethylamine

98%

Synonyme(s) :

2-Phenylethyl-N,N-dimethylamine, Dimethyl(2-phenylethyl)amine, N,N-Dimethyl-β-phenethylamine, N,N-Dimethyl-2-phenylethylamine, N,N-Dimethylbenzeneethanamine, N,N-Dimethylphenylethylamine, N-(2-Phenylethyl)dimethylamine, N-Phenethyldimethylamine, [(Dimethylamino)ethyl]benzene

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About This Item

Formule linéaire :
C6H5CH2CH2N(CH3)2
Numéro CAS:
1126-71-2
Poids moléculaire :
149.23
Numéro MDL:
MFCD00177940
Code UNSPSC :
12352100
ID de substance PubChem :
24874370
Nomenclature NACRES :
NA.22

Pureté

98%

Indice de réfraction

n20/D 1.502 (lit.)

Point d'ébullition

207-212 °C (lit.)

Densité

0.89 g/mL at 25 °C (lit.)

Chaîne SMILES 

CN(C)CCc1ccccc1

InChI

1S/C10H15N/c1-11(2)9-8-10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3

Clé InChI

TXOFSCODFRHERQ-UHFFFAOYSA-N

Catégories apparentées

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

159.8 °F - closed cup

Point d'éclair (°C)

71 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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2-Phenylethylamine for synthesis

Sigma-Aldrich

8.07334

2-Phenylethylamine

Phenethylamine 99%

Sigma-Aldrich

128945

Phenethylamine

Phenethylamine ≥99%

Sigma-Aldrich

241008

Phenethylamine

R D Schoenwald et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 14(3), 253-262 (1998-07-22)
Acini cells were obtained from the lacrimal gland of the white New Zealand rabbit. Following isolation and purification, the cells were used to study the uptake of N,N'-dimethyl-2-phenylethylamine HCl (AF2975), which was found to be sodium- and proton-independent, but energy-dependent.
S Shirolkar et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 11(1), 41-47 (1995-01-01)
In an effort to develop a long-term topically active tear stimulant, it was important to determine if tolerance developed following the repeated instillation of N,N-Dimethyl-2-phenylethylamine hydrochloride (AF2975) to the albino rabbit eye. New Zealand white rabbits were administered AF2975 (0.15%)
H Shinotoh et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 28(6), 1006-1011 (1987-06-01)
Carbon-11-labeled N,N-dimethylphenylethylamine ([11C]DMPEA) was synthesized by the reaction of N-methylphenylethylamine with [11C]methyl iodide. This newly synthesized radiotracer was developed for the purpose of in vivo measurement of monoamine oxidase-B activity in the brain using a metabolic trapping method. Initially, biodistribution
O Inoue et al.
Journal of neurochemistry, 44(1), 210-216 (1985-01-01)
N-[methyl-14C]N,N-dimethylphenylethylamine (DMPEA) was synthesized and its availability as a selective radiotracer for in vivo measurement of mouse brain monoamine oxidase (MAO) activity was examined. Relatively high incorporation of labelled DMPEA into brain (about 10% of the injected dose/per gram of
R D Schoenwald et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 14(1), 15-29 (1998-03-11)
This study was undertaken to gain an understanding of the significance of tear proteins in stabilizing the tear film. Either a sigma agonist, N,N-dimethyl-2-phenylethylamine HCl (AF2975), or a sigma antagonist, haloperidol, was administered to rabbit eyes in order to increase
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