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232505

Sigma-Aldrich

1,2-Dihydroxynaphthalene

technical grade

Synonyme(s) :

1,2-Naphthalenediol

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About This Item

Formule linéaire :
C10H6(OH)2
Numéro CAS:
574-00-5
Poids moléculaire :
160.17
Numéro CE :
209-365-2
Numéro MDL:
MFCD00003959
Code UNSPSC :
12352100
ID de substance PubChem :
24853907
Nomenclature NACRES :
NA.22

Qualité

technical grade

Pf

101-103 °C (lit.)

Chaîne SMILES 

Oc1ccc2ccccc2c1O

InChI

1S/C10H8O2/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-6,11-12H

Clé InChI

NXPPAOGUKPJVDI-UHFFFAOYSA-N

Description générale

1,2-Dihydroxynaphthalene is the most sensitive biomarker for an internal exposure to naphthalene in humans.

Application

1,2-Dihydroxynaphthalene was used as substrate to investigate the rate of oxygen consumption by washed cell suspensions of Corynebacterium sp. strain C125 grown on o-xylene, tetralin or succinate.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Katrina L Bosward et al.
Journal of dairy science, 99(3), 2142-2150 (2016-01-19)
Streptococcus agalactiae is a well-characterized bovine mastitis pathogen that is known to be highly contagious and capable of spreading rapidly in affected dairy herds. Loop-mediated isothermal amplification (LAMP) is a novel molecular diagnostic method that has the capability to provide
Muhammad Saeed et al.
Chemico-biological interactions, 165(3), 175-188 (2007-01-17)
Naphthalene is considered by the US Environmental Protection Agency to be a carcinogenic compound based on inhalation studies in rats. The primary metabolite of naphthalene is naphthalene 1,2-arene oxide. This unstable intermediate can lead to formation of 1-naphthol and naphthalene-1,2-dihydrodiol.
E Andújar et al.
Journal of bacteriology, 182(3), 789-795 (2000-01-14)
A genomic region involved in tetralin biodegradation was recently identified in Sphingomonas strain TFA. We have cloned and sequenced from this region a gene designated thnC, which codes for an extradiol dioxygenase required for tetralin utilization. Comparison to similar sequences
Sayamon Hongjaisee et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 102, 440-445 (2020-11-02)
The aim was to develop a reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for the detection of hepatitis C virus (HCV) in a single closed tube. Plasma samples were collected from 200 HCV-infected patients. HCV-RNA was detected by one-step RT-LAMP
Katrin Klotz et al.
International journal of hygiene and environmental health, 214(2), 110-114 (2010-12-15)
The possibly carcinogenic properties of naphthalene are, regarding to its ubiquitary presence, of environmental-medical and occupational-medical importance. Seven isomeric dihydroxynaphthalenes (DHN) were examined for their suitability as biomarkers in human biomonitoring and to get insights in human naphthalene metabolism. We
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