11970
1,3-Diphenyl-2-propenone
≥98.0% (GC)
Synonyme(s) :
Benzalacetophenone, Chalcone
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About This Item
Formule linéaire :
C6H5CH=CHCOC6H5
Numéro CAS:
Poids moléculaire :
208.26
Beilstein:
1210466
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
Produits recommandés
Essai
≥98.0% (GC)
Solubilité
dioxane: soluble 1 g/10 mL, clear, colorless
Groupe fonctionnel
ketone
phenyl
Chaîne SMILES
O=C(\C=C\c1ccccc1)c2ccccc2
InChI
1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+
Clé InChI
DQFBYFPFKXHELB-VAWYXSNFSA-N
Informations sur le gène
rat ... Ar(24208)
Application
1,3-Diphenyl-2-propenone was used in the preparation of pharmacologically-interesting heterocyclic systems like pyrazolines and pyrimidines.
Actions biochimiques/physiologiques
1,3-Diphenyl-2-propenone (chalcone) inhibits the proliferation of human breast cancer cell lines, MCF-7 and MDA-MB-231 by inducing apoptosis and blocking cell cycle progression in the G2/M phase. It is an inhibitor of Plasmodium falciparum cyclin-dependent protein kinases.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Équipement de protection individuelle
dust mask type N95 (US), Eyeshields, Gloves
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