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Merck

PTGER4

prostaglandin E receptor 4 (subtype EP4)

Synonymes:
EP4, EP4R
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5734) Summary: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
  • Mouse(19219) prostaglandin E receptor 4 (subtype EP4)
  • Rat(84023) prostaglandin E receptor 4 (subtype EP4)
  • sheep(101104343) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(100169968) prostaglandin E receptor 4 (subtype EP4)
  • naked mole-rat(101723705) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(101094734) prostaglandin E receptor 4 (subtype EP4)
  • domestic guinea pig(100192398) prostaglandin E receptor 4 (subtype EP4)
  • Domestic Rabbit(100009081) prostaglandin E receptor 4 (subtype EP4)
  • dog(403589) prostaglandin E receptor 4 (subtype EP4)
  • chicken(427183) prostaglandin E receptor 4 (subtype EP4)
  • sheep(443222) prostaglandin E receptor 4 (subtype EP4)
  • cow(282331) prostaglandin E receptor 4 (subtype EP4)

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Dinoprostone, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Dinoprostone, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Prostaglandin E1, ≥98% (HPLC), synthetic,
Espèce(s)
human, mouse
Prostaglandin E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
Espèce(s)
human, mouse
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Espèce(s)
human, mouse

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Prostaglandin E1, ≥98% (HPLC), synthetic,
Espèce(s)
human, mouse
Prostaglandin E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
Espèce(s)
human, mouse
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Espèce(s)
human, mouse
Prostaglandin E2, synthetic, powder, BioReagent, suitable for cell culture,
Espèce(s)
human, mouse
Prostaglandin E2, ≥93% (HPLC), synthetic,
Espèce(s)
mouse, human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PTGER4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-PE2R4 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

western blot
Anti-EP4 Prostaglandin Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
canine, human
Application
ELISA
western blot

Small Molecule - Mixed Agonist/Antagonist

Référence du produit
Description
Espèce(s)
Prostaglandin E2, ≥93% (HPLC), synthetic,
Espèce(s)
mouse, human
Indomethacin, 98.5-100.5% (in accordance with EP),
Espèce(s)
human, mouse, rat

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PTGER4,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ptger4,
Espèce(s)
mouse