HDAC4
histone deacetylase 4
Synonymes:
AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA
Espèce(s):
Human HDAC4 (9759), Mouse Hdac4 (208727), Rat Hdac4 (363287), Zebrafish hdac4 (568877), chicken HDAC4 (374207), sheep HDAC4 (101108012), fruit fly HDAC4 (32278), cow HDAC4 (517559), domestic guinea pig Hdac4 (100713301), naked mole-rat Hdac4 (101696612) ...Plus
ID UniProtKB:
ID du gène:
- Human(9759) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
- Mouse(208727) histone deacetylase 4
- Rat(363287) histone deacetylase 4
- Zebrafish(568877) histone deacetylase 4
- chicken(374207) histone deacetylase 4
- sheep(101108012) histone deacetylase 4
- fruit fly(32278) CG1770 gene product from transcript CG1770-RG
- cow(517559) histone deacetylase 4
- domestic guinea pig(100713301) histone deacetylase 4
- naked mole-rat(101696612) histone deacetylase 4
- dog(607662) histone deacetylase 4
- domestic cat(101093384) histone deacetylase 4
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-HDAC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-HDAC4 (Ab-632) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
western blot
western blot
Anti-phospho-HDAC4 (pSer632) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-HDAC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorps anti-HDAC4, serum, from rabbit,
Espèces réactives
human
Application
ChIP
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Proteins
Référence du produit
Description
Espèce(s)
HDAC-4 human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
Espèce(s)
human