Accéder au contenu
Merck

GZMB

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

Synonymes:
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Espèce(s):
Human GZMB (3002), Mouse Gzmb (14939), Rat Gzmb (171528), domestic guinea pig Gzmb (100736180), dog GZMB (490630), cow GZMB (508646), cow GZMB (281731), Horse GZMB (100033978), domestic cat GZMB (100127106), naked mole-rat Gzmb (101702156)
ID UniProtKB:
P10144, Q8N1D2, Q9UCC1
ID du gène:
  • Human(3002) Summary: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]
  • Mouse(14939) granzyme B
  • Rat(171528) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic guinea pig(100736180) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • dog(490630) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(508646) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(281731) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • Horse(100033978) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic cat(100127106) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • naked mole-rat(101702156) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Référence du produit
Description
Espèce(s)
RAB0210
Mouse Granzyme B ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse
RAB1498
Human Granzyme B ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
MAB3070
Anticorps anti-granzyme B, clone GrB-7, culture supernatant, clone GrB-7, Chemicon®,
Espèces réactives
human
Application
immunohistochemistry
western blot
HPA003418
Anti-GZMB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
SAB4700295
Monoclonal Anti-GZMB antibody produced in mouse, clone CLB-GB11, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, nonhuman primates
Application
flow cytometry
ZRB2736
Anti-Granzyme B Antibody, clone 3M4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
ELISA
affinity binding assay
flow cytometry
western blot
SAB4501359
Anti-Granzyme B antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
SRE0021
Granzyme B human, recombinant, expressed in insect cells, ≥90% (SDS-PAGE),
Espèce(s)
human
SRP3202
Granzyme B from mouse, recombinant, expressed in Hi-5 Insect cells, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture,
Espèce(s)
mouse

esiRNA

Référence du produit
Description
Espèce(s)
EHU106641
MISSION® esiRNA, targeting human GZMB,
Espèce(s)
human

Small Molecule - Substrate

Référence du produit
Description
Espèce(s)
A6470
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide, ≥97% (HPLC), powder,
Espèce(s)
rat, mouse, human
A9968
N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide, ≥95%,
Espèce(s)
rat, mouse, human
A4188
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,
Espèce(s)
rat, mouse, human
A6220
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, ≥97% (HPLC), powder,
Espèce(s)
rat, mouse, human