CXCR4
chemokine (C-X-C motif) receptor 4
Synonymes:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Espèce(s):
Human CXCR4 (7852), Mouse Cxcr4 (12767), Rat Cxcr4 (60628), cow CXCR4 (281736), domestic guinea pig Cxcr4 (100731341), dog CXCR4 (483900), naked mole-rat Cxcr4 (101699254), sheep CXCR4 (443532), chicken CXCR4 (395324), Domestic Rabbit CXCR4 (100346189)
ID UniProtKB:
ID du gène:
- Human(7852) Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(12767) chemokine (C-X-C motif) receptor 4
- Rat(60628) chemokine (C-X-C motif) receptor 4
- cow(281736) chemokine (C-X-C motif) receptor 4
- domestic guinea pig(100731341) chemokine (C-X-C motif) receptor 4
- dog(483900) chemokine (C-X-C motif) receptor 4
- naked mole-rat(101699254) chemokine (C-X-C motif) receptor 4
- sheep(443532) neuropeptide Y receptor type 3
- chicken(395324) chemokine (C-X-C motif) receptor 4
- Domestic Rabbit(100346189) chemokine (C-X-C motif) receptor 4
- domestic cat(493676) chemokine (C-X-C motif) receptor 4
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-C-X-C Chemokine Receptor 4 Antibody, NT, Chemicon®, from rabbit,
Espèces réactives
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CXCR4 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, mouse
Application
ELISA
flow cytometry
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
flow cytometry
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-CXCR4 Antibody, clone 12G5, clone 12G5, from mouse,
Espèces réactives
human
Application
flow cytometry
immunocytochemistry
neutralization
immunocytochemistry
neutralization
Monoclonal Anti-CXCR4 antibody produced in mouse, clone 1F8, ascites fluid,
Espèces réactives
human
Application
ELISA
western blot
western blot
Anti-CXCR4 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
western blot
Proteins
Référence du produit
Description
Espèce(s)
ChemiSCREEN CXCR4 Membrane Preparation, Human CXCR4 GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,
Espèce(s)
human