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Merck

CSF1R

colony stimulating factor 1 receptor

Synonymes:
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1436) Summary: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(12978) colony stimulating factor 1 receptor
  • Rat(307403) colony stimulating factor 1 receptor
  • domestic guinea pig(100726053) colony stimulating factor 1 receptor
  • naked mole-rat(101719513) colony stimulating factor 1 receptor
  • sheep(101109969) colony stimulating factor 1 receptor
  • cow(509418) colony stimulating factor 1 receptor
  • domestic cat(493706) colony stimulating factor 1 receptor
  • Horse(100060422) colony stimulating factor 1 receptor
  • dog(489188) colony stimulating factor 1 receptor
  • chicken(396406) colony stimulating factor 1 receptor

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Espèce(s)
human
Phosphotyrosine CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-CSF-1R antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP211, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
Anti-CSF1R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anticorps anti-CSF-1R/CD115, clone FER216, clone FER216, from mouse,
Espèces réactives
human
Application
western blot
Monoclonal Anti-CSF1R antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL11653, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
Anti-CSF1R/c-FMS Antibody, clone AFS98, ,
Espèces réactives
mouse
Application
flow cytometry

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Pazopanib, ,
Espèce(s)
human

Proteins

Numéro du produit
Description
Espèce(s)
FMS (539-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Csf1r,
Espèce(s)
mouse
MISSION® esiRNA, targeting human CSF1R,
Espèce(s)
human