CASP3
caspase 3, apoptosis-related cysteine peptidase
Synonymes:
CPP32, CPP32B, SCA-1
Espèce(s):
Human CASP3 (836), Mouse Casp3 (12367), Rat Casp3 (25402), dog CASP3 (403567), chicken CASP3 (395476), naked mole-rat Casp3 (101712867), domestic guinea pig Casp3 (100718309), cow CASP3 (408016), Domestic Rabbit CASP3 (100008840), sheep CASP3 (443031) ...Plus
ID UniProtKB:
ID du gène:
- Human(836) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
- Mouse(12367) caspase 3
- Rat(25402) caspase 3
- dog(403567) caspase 3, apoptosis-related cysteine peptidase
- chicken(395476) caspase 3, apoptosis-related cysteine peptidase
- naked mole-rat(101712867) caspase 3, apoptosis-related cysteine peptidase
- domestic guinea pig(100718309) caspase 3, apoptosis-related cysteine peptidase
- cow(408016) caspase 3, apoptosis-related cysteine peptidase
- Domestic Rabbit(100008840) caspase 3, apoptosis-related cysteine peptidase
- sheep(443031) caspase 3, apoptosis-related cysteine peptidase
- domestic cat(493932) caspase 3, apoptosis-related cysteine peptidase
- Horse(100034083) caspase 3, apoptosis-related cysteine peptidase
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Activity Assay
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anticorps anti-caspase-3, forme active (clivée), Chemicon®, from rabbit,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CASP3 (p17, Cleaved-Asp175) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
western blot
Anticorps anti-caspase 3, from rabbit, purified by affinity chromatography,
Espèces réactives
canine, feline, hamster, human, mouse, nonhuman primates, rat
Application
immunocytochemistry
western blot
western blot
Anti-Caspase-3 Antibody, clone 3J16 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, human, mouse, rat
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-Caspase 3 Antibody, Upstate®, from rabbit,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Kits
Référence du produit
Description
Espèce(s)
Caspase 3 Colorimetric Activity Assay Kit, DEVD, Caspase-3 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the sequence DEVD.,
Espèce(s)
human
CaspaTag Caspase 3,7 In Situ Assay Kit, Fluorescein, The In Situ Caspase Detection Kit for Flow Cytometry use a novel approach to detect active caspases. The methodology is based on Fluorochrome Inhibitors of Caspases (FLICA).,
Espèce(s)
human
Caspase 3 Colorimetric Activity Assay Kit, DEVD, Caspase-3 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the sequence DEVD.,
Espèce(s)
human
CaspaTag Caspase 3,7 In Situ Assay Kit, Fluorescein, The CaspaTag Caspase-3/7 In Situ Assay Kit, Fluorescein for Flow Cytometry is a fluorescent-based assay for detection of active caspase-3 or caspase-7 in cells undergoing apoptosis.,
Espèce(s)
human
Proteins
Référence du produit
Description
Espèce(s)
Caspase 3 human, ≥90% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous glycerol solution, ≥1.0 units/mg protein,
Espèce(s)
human
esiRNA
Référence du produit
Description
Espèce(s)