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Merck

BAG3

BCL2-associated athanogene 3

Synonymes:
BAG-3, BIS, CAIR-1, MFM6
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(9531) Summary: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
  • Mouse(29810) BCL2-associated athanogene 3
  • Rat(293524) Bcl2-associated athanogene 3
  • chicken(423931) BCL2-associated athanogene 3
  • sheep(101108530) BCL2-associated athanogene 3
  • Zebrafish(445139) BCL2-associated athanogene 3
  • Thale Cress(830613) BCL-2-associated athanogene 3
  • domestic guinea pig(100715844) BCL2-associated athanogene 3
  • naked mole-rat(101716547) BCL2-associated athanogene 3
  • Horse(100065784) BCL2-associated athanogene 3
  • domestic cat(101094211) BCL2-associated athanogene 3
  • dog(486916) BCL2-associated athanogene 3
  • cow(782633) BCL2-associated athanogene 3

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-BAG3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BAG3 Antibody, clone AC-1, clone AC-1, from mouse,
Espèces réactives
human
Application
immunohistochemistry
immunoprecipitation (IP)
Anti-BAG3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-BAG3 antibody produced in mouse, clone 5A8, ascites fluid,
Espèces réactives
human
Application
ELISA
western blot
Anti-BAG3 antibody produced in rabbit, ,
Espèces réactives
mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human BAG3,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Bag3,
Espèce(s)
mouse