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Merck

BAD

BCL2-associated agonist of cell death

Synonymes:
BBC2, BCL2L8
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
2,3-Dihydroxynaphthalene, ≥98.0% (HPLC),
Espèce(s)
human
4-Biphenylacetic acid, 98%,
Espèce(s)
human
Biphenyl-4-carboxylic acid, 95%,
Espèce(s)
human
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-BAD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BAD antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho BAD Antibody (Ser155), from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, canine, human, mouse, rat
Application
immunoprecipitation (IP)
inhibition assay

western blot
Anti-BAD (Ab-136) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-BAD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

Proteins

Référence du produit
Description
Espèce(s)
BAD, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human BAD,
Espèce(s)
human