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SML2554

Sigma-Aldrich

RIPK2 inhibitor 1

≥98% (HPLC)

Synonym(s):

3-(Benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]-benzamide, MolPort-016-359-762

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About This Item

Empirical Formula (Hill Notation):
C25H22N4O2
CAS Number:
Molecular Weight:
410.47
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to very dark gray

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=CC=C(C(NC2=CC(C3=NC=CN3C)=CC=C2)=O)C=C1NC(C4=CC=CC=C4)=O

Biochem/physiol Actions

RIPK2 inhibitor 1 is a potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) that potently inhibit NFκB activity and the proliferation of cancer cell lines. RIPK2 inhibitor 1 inhibits intestinal and lung inflammation in rodent models.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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