SML0463

BPD

≥98% (HPLC)

• Synonym(s): 3-(1,3-benzodioxol-5-yl)-4-phenyl-2,5-Furandione
• Empirical Formula (Hill Notation): C₁₇H₁₀O₅
• CAS Number: 213481-12-0
• Molecular Weight: 294.26
• MDL number: MFCD22666591
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824741

Properties

• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 15 mg/mL (clear solution)
• storage temp.: −20°C
• SMILES string: O=C1OC(=O)C(c2ccc3OCOc3c2)=C1c4ccccc4
• InChI: 1S/C17H10O5/c18-16-14(10-4-2-1-3-5-10)15(17(19)22-16)11-6-7-12-13(8-11)21-9-20-12/h1-8H,9H2
• InChI key: IMHGOAWBSJVILI-UHFFFAOYSA-N

Description

Biochem/physiol Actions

BPD inhibits LPS-induced NF-kB signaling by inactivation of TAK-1. BPD is also known to inhibit the expression and activity of COX-2.

Features and Benefits

This compound is featured on the Cytokine Receptors (Interleukin-1 Receptor/TIR Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H400
• Precautionary Statements: P273
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable