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SAB5200222
Monoclonal Anti-Kcc2 antibody produced in mouse
clone S1-12, purified immunoglobulin
Synonym(s):
Anti-Electroneutral potassium chloride cotransporter 2, Anti-Potassium Chloride Cotransporter, Anti-SLC12A5, Anti-hKCC2
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100 μG
CHF 412.00
CHF 412.00
Estimated to ship on15 April 2025
A recombinant, preservative-free antibody is available for your target. Try ZRB1273
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100 μG
CHF 412.00
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
CHF 412.00
Estimated to ship on15 April 2025
A recombinant, preservative-free antibody is available for your target. Try ZRB1273
Recommended Products
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
S1-12, monoclonal
form
buffered aqueous solution
mol wt
antigen predicted mol wt 140 kDa
species reactivity
mouse, human, rat
concentration
1 mg/mL
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Slc12a5(171373)
Specificity
Detects ~140kDa.
Immunogen
Fusion protein amino acids 932-1043 corresponding to rat KCC2
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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recommended
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Lulan Chen et al.
Scientific reports, 7(1), 156-156 (2017-03-11)
GABAA receptor-mediated inhibition depends on the maintenance of low level intracellular [Cl-] concentration, which in adult depends on neuron specific K+-Cl- cotransporter-2 (KCC2). Previous studies have shown that KCC2 was downregulated in both epileptic patients and various epileptic animal models.
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Can you specify about sample preparation as we are able to see bands at 42kDa when probed using this antibody. Can you provide details on it
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