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SAB4500347

Sigma-Aldrich

Anti-Histone H3 (Acetyl-Lys9) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

H3/a, H3/c, H3/d, H3/f, H3/h

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 15 kDa

species reactivity

human, rat, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

P68431

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

acetylation (Lys9)

Gene Information

human ... HIST1H3A(8350)

Related Categories

General description

Anti-Histone H3 (Acetyl-Lys9) Antibody detects endogenous levels of total Histone H3 (Acetyl-Lys9) protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human Histone H3 around the acetylated site of Lys9.

Immunogen Range: 3-52

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Epigenetic and Neuronal Activity Markers Suggest the Recruitment of the Prefrontal Cortex and Hippocampus in the Three-Hit Model of Depression in Male PACAP Heterozygous Mice.
Gaszner, et al.
International Journal of Molecular Sciences, 23 (2022)
Tamás Gaszner et al.
Frontiers in endocrinology, 13, 995900-995900 (2022-10-11)
According to the three hit concept of depression, interaction of genetic predisposition altered epigenetic programming and environmental stress factors contribute to the disease. Earlier we demonstrated the construct and face validity of our three hit concept-based mouse model. In the
Kornél Demeter et al.
Behavioural brain research, 300, 123-134 (2015-12-26)
Schizophrenia-like symptoms were detected in vasopressin-deficient (di/di) Brattleboro rats, and it was also suggested that schizophrenia might have an epigenetic component. We aimed to clarify if epigenetic changes contribute to schizophrenia-like behavior of this strain. Behavioral (locomotion by telemetry, cognition
Katja Merschbaecher et al.
Learning & memory (Cold Spring Harbor, N.Y.), 23(2), 83-89 (2016-01-17)
Acetylation of histones changes the efficiency of the transcription processes and thus contributes to the formation of long-term memory (LTM). In our comparative study, we used two inhibitors to characterize the contribution of different histone acetyl transferases (HATs) to appetitive
Svetlana Demyanenko et al.
International journal of molecular sciences, 20(12) (2019-06-16)
Ischemic penumbra that surrounds a stroke-induced infarction core is potentially salvageable; however, mechanisms of its formation are not well known. Covalent modifications of histones control chromatin conformation, gene expression and protein synthesis. To study epigenetic processes in ischemic penumbra, we

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