Bad antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bad.
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The action of this antibody can be blocked using blocking peptide SBP3500336.
The serine/threonine Pim kinases are overexpressed in various types of solid carcinomas and hematological malignancies, and contribute to regulating cell-cycle progression and cell survival. The aim of this study was to discover a novel pan-Pim kinases inhibitor with potent anti-proliferative
Frontiers in pharmacology, 12, 672536-672536 (2021-05-21)
Pim kinases are overexpressed in various types of hematological malignancies and solid carcinomas, and promote cell proliferation and survival. Here in this study, we investigated the preclinical profile of novel pan-Pim kinase inhibitors with imidazopyridazine and thiazolidinedione structure. Imidazopyridazine-thiazolidinediones inhibited
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