Synthetic peptide directed towards the N terminal region of human ONECUT1
Biochem/physiol Actions
ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5′-DHWATTGAYTWWD-3′ on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Sequence
Synthetic peptide located within the following region: NAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPR
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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