Similar to other class III myosins, MYO3B contains an N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3B gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis showed expression of a 7-kb MYO3B transcript in human retina, but not in an RPE cell line; two 6- and 7-kb MYO3B transcripts in kidney; and a 4-kb transcript in testis.
Immunogen
MYO3B (NP_620482, 536-570) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MYO3B.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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