S7635

Sulforhodamine 101

Dye content ~95 %, Powder

• Synonym(s): SR101; 2-(3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaen-16-yl)-5-sulfobenzenesulfonate
• Empirical Formula (Hill Notation): C₃₁H₃₀N₂O₇S₂
• CAS Number: 60311-02-6
• Molecular Weight: 606.71
• Beilstein: 3582548
• EC Number: 262-159-4
• MDL number: MFCD00012407
• UNSPSC Code: 12171500
• PubChem Substance ID: 24899749
• NACRES: NA.47

Properties

• Product Name: Sulforhodamine 101, Dye content ~95 %
• form: powder
• Quality Level: 100
• composition: Dye content, ~95%
• technique(s): microbe id | staining: suitable
• color: black; dark green to brown
• solubility: methanol: 1 mg/mL
• ε (extinction coefficient): ≥105000 at 573-579 nm in ethanol
• fluorescence: λ_ex 586 nm; λ_em 605 nm in H₂O
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: OS(=O)(=O)c1ccc(C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)c(c1)S([O-])(=O)=O
• InChI: 1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)
• InChI key: COIVODZMVVUETJ-UHFFFAOYSA-N

Description

General description

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine.[1]

Application

Sulforhodamine 101 has been used:

• to label astrocytes[2]
• in quantitative polymerase chain reaction (PCR)[3]
• to determine the degree of disintegration in tissue sample[4]

Biochem/physiol Actions

Sulforhodamine 101 can be specifically used as a marker of astroglia in the neocortex.[1] It is commonly used for brain imaging.[5] Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.[6]

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves