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Key Documents

RAB1108

Sigma-Aldrich

Rabbit IL-1 beta ELISA Kit

for cell culture supernatants, plasma, and serum samples

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

rabbit

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type serum sample(s)
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/ml

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

rabbit ... IL1B(100008990)

General description

This enzyme-linked immunosorbent assay (ELISA) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of a target protein in biological samples, such as serum, plasma, cell culture supernatants, urine and/or cell and tissue lysates.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

Interleukin 1 beta (IL-1β) is a proinflammatory cytokine, which is implicated in the induction of various acute and chronic inflammation. IL1B is considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. Mutations in IL-1β gene are linked with renal manifestations and renal sequelae in Henoch-Schönlein purpura (HSP).

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Eric G Romanowski et al.
Infection and immunity, 89(8), e0011121-e0011121 (2021-04-07)
In this study, we tested the hypothesis that the conserved bacterial IgaA-family protein, GumB, mediates microbial pathogenesis associated with Serratia marcescens ocular infections through regulation of the Rcs stress response system. The role of the Rcs system and bacterial stress
Interleukin 1 beta (IL1) rs16944 genetic variant as a genetic marker of severe renal manifestations and renal sequelae in Henoch-Schonlein purpura.
Lopez MR, et al.
Clinical and Experimental Rheumatology, S84-S88 (2016)
Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis.
Kolb M
The Journal of Clinical Investigation, 107(12), 1529-1536 (2001)

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