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R7753

Sigma-Aldrich

Rhapontin

≥99% (HPLC), from rhubarb

Synonym(s):

3,3′,5-Trihydroxy-4′-methoxystilbene 3-O-β-D-glucoside, NSC 43321, Rhaponticin

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About This Item

Empirical Formula (Hill Notation):
C21H24O9
CAS Number:
155-58-8
Molecular Weight:
420.41
EC Number:
205-845-0
MDL number:
MFCD00010117
UNSPSC Code:
12352201
PubChem Substance ID:
24899400

biological source

rhubarb

Assay

≥99% (HPLC)

storage temp.

2-8°C

SMILES string

COc1ccc(\C=C\c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1O

InChI

1S/C21H24O9/c1-28-16-5-4-11(8-15(16)24)2-3-12-6-13(23)9-14(7-12)29-21-20(27)19(26)18(25)17(10-22)30-21/h2-9,17-27H,10H2,1H3/b3-2+/t17-,18-,19+,20-,21-/m1/s1

InChI key

GKAJCVFOJGXVIA-DXKBKAGUSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hyung Jun Lim et al.
Journal of colloid and interface science, 320(2), 460-468 (2008-02-12)
It is known that cyclodextrins (CDs) extract lipid components from bilayer of liposomes. This could undermine the potential benefits of liposomes as drug carriers. In this study, we demonstrated that PC-Chol liposomes with various CDs or rhapontin (Rh)-hydroxypropyl betaCD (HPbetaCD)
Fang-Fang Chen et al.
Journal of chromatography. A, 1252, 8-14 (2012-07-11)
The magnetic molecularly imprinted polymers (MMIPs) had been synthesized for the selective extraction and clean-up of rhaponticin in Chinese patent medicines (CPM). The MMIPs were prepared via suspension polymerization, using Fe(3)O(4) as magnetically component, rhaponticin as template molecule, acrylamide (AM)
Jeong-Keun Kim et al.
Journal of microbiology and biotechnology, 20(1), 82-87 (2010-02-06)
Biotransformation is often used to improve chemical activity. We evaluated the antimicrobial activity of rhapontigenin, converted from rhapontin after treatment with Pectinex. Rhapontigenin showed 4-16 times higher antimicrobial activity than rhapontin. Activity was higher against Gram positive strains than Gram
Xuhua Liang et al.
Bioorganic & medicinal chemistry, 21(1), 178-185 (2012-11-28)
To improve the therapeutic effect of rhaponticin (RHA), a folate receptor (FR) targeted RHA conjugate was synthesized by utilizing a hydrophilic peptide spacer linked to folic acid (FA) via a releasable disulfide linker. This water-soluble conjugate was found to retain
Yang Sun et al.
Journal of nanoscience and nanotechnology, 12(10), 7677-7684 (2013-02-21)
Rhaponticin (RA) extracted from many medicinal plants has been demonstrated to possess a variety of pharmacological activities including potent antitumor, antitumor-promoting, antithrombotic, antioxidant and vasorelaxant activities. However, its poor solubility and bioavailability restricted the clinical application greatly. In this work
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