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P5171

Sigma-Aldrich

Endoproteinase Arg-C from mouse submaxillary gland

Type XX-S, lyophilized powder, 250-800 units/mg protein (Lowry)

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About This Item

CAS Number:
Enzyme Commission number:
EC Number:
MDL number:
UNSPSC Code:
12352204

type

Type XX-S

Quality Level

form

lyophilized powder

specific activity

250-800 units/mg protein (Lowry)

composition

Protein, 3.0-7.0%

analyte chemical class(es)

amino acids

storage temp.

2-8°C

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Unit Definition

One unit will hydrolyze 1.0 μmole of Nα-p-tosyl-L-arginine methyl ester per min at pH 8.0 at 25 °C.

Physical form

Lyophilized powder containing NaCl and sodium acetate

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


Certificates of Analysis (COA)

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Michael E Stern et al.
Investigative ophthalmology & visual science, 53(4), 2062-2075 (2012-03-08)
The purpose of this study was to determine if autoantibodies play a role in the immunopathogenesis of experimental dry eye disease. Dry eye was induced by exposing female C57BL/6 wild-type mice or hen egg lysozyme B-cell receptor transgenic mice to
Yoshika Yasuda et al.
Biological & pharmaceutical bulletin, 34(9), 1518-1521 (2011-09-02)
Oral formulation of tissue kallikrein consists primarily of porcine pancreatic kallikrein (PPK) and is used to improve peripheral circulation, menopausal symptoms, and impaired chorioretinal circulation. Although gastrointestinal absorption of tissue kallikrein after oral administration has been reported in nonclinical and
Ling Liu et al.
Biochemical and biophysical research communications, 407(2), 283-287 (2011-03-08)
Systemic or local delivery of human tissue kallikrein gene (hTK) has been shown to be an effective strategy to alleviate cerebral ischemia/reperfusion (I/R) injury, and tissue kallikrein (TK) administration can suppress glutamate- or acidosis-mediated neurotoxicity in vitro. In the present
Waleska K Martins et al.
BMC medical genomics, 4, 76-76 (2011-10-29)
A wide variety of high-throughput microarray platforms have been used to identify molecular targets associated with biological and clinical tumor phenotypes by comparing samples representing distinct pathological states. The gene expression profiles of human cutaneous melanomas were determined by cDNA
Yi-Dong Wang et al.
European neurology, 65(4), 208-214 (2011-03-23)
Kallikrein, a serine proteinase, has been reported to have many functions, such as selectively dilating arterioles in the ischemic area and enhancing angiogenesis and neurogenesis. Therefore, it may promote cerebral poststroke reorganization. We observed the effect of human tissue kallikrein

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