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About This Item
Empirical Formula (Hill Notation):
C6H8N2O8
CAS Number:
Molecular Weight:
236.14
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
form
powder
contains
~60% lactose
color
white
solubility
organic solvents: soluble (alcohol, acetone and ether)
SMILES string
[H][C@@]1([C@@]([H])(O[N+]([O-])=O)CO2)[C@@]2([H])[C@]([H])(O[N+]([O-])=O)CO1
InChI
1S/C6H8N2O8/c9-7(10)15-3-1-13-6-4(16-8(11)12)2-14-5(3)6/h3-6H,1-2H2
InChI key
MOYKHGMNXAOIAT-UHFFFAOYSA-N
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Biochem/physiol Actions
Nitric oxide (NO) donor and nitrovasodilator. Induces stimulation of corpus mucin biosynthesis in vivo. Used to study the role of nitric oxide in the control of cell growth.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Desen. Expl. 3
Storage Class Code
4.1A - Other explosive hazardous materials
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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S Fujii et al.
The American journal of physiology, 274(5 Pt 1), G857-G862 (1998-06-05)
Recently, in vivo electron paramagnetic resonance (EPR) spectroscopy and imaging have been widely used to investigate free radical distribution and metabolism in tissues, organs, and whole body of small animals. Endogenous nitric oxide (NO) is an attractive target of this
C Sciorati et al.
British journal of pharmacology, 122(4), 687-697 (1998-01-10)
1. The role of nitric oxide (NO) in the control of cell growth is controversial since both stimulation and (more often) inhibition have been demonstrated in various cell types. In order to reinvestigate the problem and identify the sites of
Benjamin Medalion et al.
The Journal of thoracic and cardiovascular surgery, 150(3), 607-612 (2015-07-21)
Bilateral internal thoracic artery grafting in elderly patients is controversial. We compared the outcome of bilateral internal thoracic artery grafting with that of single internal thoracic artery and saphenous vein and radial artery conduits in these patients. Patients aged 70 years
S Silber
European journal of clinical pharmacology, 38 Suppl 1, S35-S51 (1990-01-01)
Nitrates are highly effective both in terminating acute attacks of angina pectoris and in the prophylaxis of symptomatic and asymptomatic myocardial ischemia. Preload reduction by venodilatation is the prevailing mechanism of nitrates in patients with chronic stable angina and is
C R Conti et al.
American heart journal, 110(1 Pt 2), 251-256 (1985-07-01)
The efficacy of isosorbide dinitrate (ISDN) in variant angina is enhanced by the addition of a calcium antagonist. A prospective double-blind, crossover trial of ISDN, 40 to 120 mg/day, and nifedipine, 40 to 120 mg/day, in 19 patients with variant
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