Skip to Content
Merck
All Photos(4)

Documents

H1252

Sigma-Aldrich

Homovanillic acid

>99% purity (TLC), powder

Synonym(s):

4-Hydroxy-3-methoxyphenylacetic acid, HVA

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
HOC6H3(OCH3)CH2CO2H
CAS Number:
Molecular Weight:
182.17
Beilstein:
2213447
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Homovanillic acid, Fluorimetric reagent

Assay

>99% (TLC)

form

powder

color

white to off-white

mp

142-145 °C (lit.)

solubility

ethanol: 50 mg/mL, colorless to light yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

COc1cc(CC(O)=O)ccc1O

InChI

1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)

InChI key

QRMZSPFSDQBLIX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Homovanillic acid has been used as a standard in HPLC analysis.

Biochem/physiol Actions

Metabolite of dihydroxyphenylacetic acid (DOPAC) by catechol O-methyltransferase; reagent for the fluorimetric determination of glucose oxidase and other oxidative enzymes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Tashjian AH and Armstrong EJ
Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy (2011)
Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease.
Tillerson JL
Neuroscience, 119, 899-899 (2003)
Practical Fluorescence (1990)
Forced nonuse in unilateral parkinsonian rats exacerbates injury.
Tillerson JL
The Journal of Neuroscience, 22, 6790-6790 (2002)
S J Kish et al.
Journal of neurochemistry, 58(2), 642-648 (1992-02-01)
To examine the possible causal contribution of normal or accelerated aging to the neurodegenerative process of Parkinson's disease, we measured the influence of aging on subregional striatal dopamine and homovanillic acid levels in postmortem brain of 23 neurologically and psychiatrically

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service