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G9398

Sigma-Aldrich

Asialoganglioside-GM2 from bovine brain

~95%, lyophilized powder

Synonym(s):

GA2 Ganglioside, Gangliotriosyl ceramide

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.77

Assay

~95%

Quality Level

form

lyophilized powder

storage temp.

−20°C

General description

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

Biochem/physiol Actions

Degraded form of Asialoganglioside-GM1 ganglioside.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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K Kanai et al.
The Southeast Asian journal of tropical medicine and public health, 28(4), 781-790 (1998-07-10)
Specific binding between bacterial cells and host tissue is an early step of the pathogenesis of infection. Burkholderia pseudomallei cells, the causative micro-organisms of melioidosis, were demonstrated to bind specifically to tissue glycolipids (asialo GM1 and asialo GM2) by solid
W Möbius et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 47(8), 1005-1014 (1999-07-29)
A radioactive and biotin-labeled analogue of GM1 (biotin-GM1) was synthesized which enabled us to analyze its intracellular distribution in the compartments of the endocytic route by electron microscopic immunocytochemistry using thin sections of human skin fibroblasts labeled with gold-conjugated antibiotin
K Tadano-Aritomi et al.
Glycoconjugate journal, 13(2), 285-293 (1996-04-01)
A novel mono-sulfated glycosphingolipid based on the gangliotriaose core structure was isolated from rat kidney. The isolation procedure involved extraction of lipids with chloroform/methanol, mild alkaline methanolysis, column chromatographies with anion exchangers and silica beads. The structure was characterized by
Aufaugh Emam et al.
Microbiology (Reading, England), 152(Pt 9), 2789-2799 (2006-09-02)
The glycosphingolipids (GSLs) gangliotriaosylceramide (Gg(3)) and gangliotetraosylceramide (Gg(4)) have been implicated as receptors for type IV pili (T4P)-mediated Pseudomonas aeruginosa epithelial cell attachment. Since P. aeruginosa T4P are divided into five groups, the authors determined whether GSLs in general, and
Annelies Coddens et al.
PloS one, 6(9), e23309-e23309 (2011-09-29)
Enterotoxigenic F4-fimbriated Escherichia coli is associated with diarrheal disease in neonatal and postweaning pigs. The F4 fimbriae mediate attachment of the bacteria to the pig intestinal epithelium, enabling an efficient delivery of diarrhea-inducing enterotoxins to the target epithelial cells. There

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