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EHU081311

Sigma-Aldrich

MISSION® esiRNA

targeting human NEIL1

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20 μG
CHF 249.00
50 μG
CHF 443.00

CHF 249.00


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Estimated to ship on16 February 2025



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20 μG
CHF 249.00
50 μG
CHF 443.00

About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

CHF 249.00


Availability

Estimated to ship on16 February 2025


description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCCCTATGTTTCGTGGACATCCGCCGGTTCGGCCGCTGGGACCTTGGGGGAAAGTGGCAGCCGGGCCGCGGGCCCTGTGTCTTGCAGGAGTACCAGCAGTTCAGGGAGAATGTGCTACGAAACCTAGCGGATAAGGCCTTTGACCGGCCCATCTGCGAGGCCCTCCTGGACCAGAGGTTCTTCAATGGCATTGGCAACTATCTGCGGGCAGAGATCCTGTACCGGCTGAAGATCCCCCCCTTTGAGAAGGCCCGCTCGGTCCTGGAGGCCCTGCAGCAGCACAGGCCGAGCCCGGAGCTGACCCTGAGCCAGAAGATAAGGACCAAGCTGCAGAATCCAGACCTGCTGGAGCTATGTCACTCAGTGCCCAAGGAAGTGGTCCAGTTGGGGGGCAAAGGCTACGGGTCAGAGAGCGGGGAGGAGGACTTTGCTGCCTTT

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

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EHU028271EHU024861EHU026861
Ensembl | human accession no.

ENSG00000140398

Ensembl | human accession no.

ENSG00000151576

Ensembl | human accession no.

ENSG00000067836

Ensembl | human accession no.

ENSG00000111058

esiRNA cDNA target sequence

GCCCTATGTTTCGTGGACATCCGCCGGTTCGGCCGCTGGGACCTTGGGGGAAAGTGGCAGCCGGGCCGCGGGCCCTGTGTCTTGCAGGAGTACCAGCAGTTCAGGGAGAATGTGCTACGAAACCTAGCGGATAAGGCCTTTGACCGGCCCATCTGCGAGGCCCTCCTGGACCAGAGGTTCTTCAATGGCATTGGCAACTATCTGCGGGCAGAGATCCTGTACCGGCTGAAGATCCCCCCCTTTGAGAAGGCCCGCTCGGTCCTGGAGGCCCTGCAGCAGCACAGGCCGAGCCCGGAGCTGACCCTGAGCCAGAAGATAAGGACCAAGCTGCAGAATCCAGACCTGCTGGAGCTATGTCACTCAGTGCCCAAGGAAGTGGTCCAGTTGGGGGGCAAAGGCTACGGGTCAGAGAGCGGGGAGGAGGACTTTGCTGCCTTT

esiRNA cDNA target sequence

TGGTGAGAGGATGTTCCTGTTACTGCTGTAAGAATCACACTCGGGCATACATCCACCATCTGCTGGTGACCAATGAGCTGCTGGCCGGAGTCCTGCTTATGATGCACAACTTTGAACACTACTTTGGGTTTTTCCATTACATCCGGGAAGCACTAAAAAGTGACAAACTGGCACAGTTGAAAGAGCTCATCCACAGGCAAGCATCTTGAGATCTTGCAAATACAAGTCTCACTCTTCACACTGAGCCTGTACCACTGTTGTAACATGGGAAGACGTGAAGAAGAAATAATCTGAGCTTTAATTATTTATATTTGGATATAAGGTCTGCTTAAATAAAGAATCTTTGTACCAAACTGCCCACATGAGGGTGAAGAGATTTCCTCAAAAGACTTAAATGACCTGGATTGATCAGAGAGA

esiRNA cDNA target sequence

CCTGCTGGTCAACGTCTACATCAACCTCAACAAGCTCTGCCTCACGGTGTACCAGCTGCATGCCCTGCAGCCCAACTCCACCAAGAACTTCCGCCCAGCTGGGGGCGCGGTGCTGCATAGCCCTGGGGCCATGTTCGAGTGGGGCTCTCAGCGCCTGGAGGTGAGCCACGTGCACAAAGTGGAGTGCGTGATCCCCTGGCTCAACGACGCCCTGGTCTACTTCACCGTCTCCCTGCAGCTCTGCCAGCAGCTCAAGGACAAGATCTCCGTGTTCTCCAGCTACTGGAGCTACAGACCCTTCTGATCACAGCACCCAGGAGCTTGTCTCCAGGAAGGCGGCCCCGTCCCCTACTCATACCCACCACAGAGCACCAGCCAGTGCCAACGCCAGGCTGCTATTTATCTCCCTATCCCACCCC

esiRNA cDNA target sequence

GGTGGTTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGTTGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGCTATCATCTATGACAGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAAAGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTTGGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTATGATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAGGATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACTAAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGTTACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACTTGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGACAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGGTTCCTT

Gene Information

human ... NEIL1(79661), NEIL1(79661)

Gene Information

human ... QTRT2(79691), QTRTD1(79691)

Gene Information

human ... ROGDI(79641), ROGDI(79641)

Gene Information

human ... ACSS3(79611), ACSS3(79611)

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

NCBI accession no.

NM_024608

NCBI accession no.

NM_024638

NCBI accession no.

NM_024589

NCBI accession no.

NM_024560

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Wanjuan Xue et al.
BioMed research international, 2020, 5053975-5053975 (2020-07-21)
The study is aimed at investigating the role of Nei endonuclease VIII-like1 (NEIL1) in the pathogenesis of colorectal cancer (CRC). The human CRC (HCT116 and SW480) cells were subjected to the siRNA silencing and recombinant plasmid overexpression of NEIL1. Transfection
Shiladitya Sengupta et al.
DNA repair, 66-67, 1-10 (2018-04-27)
Posttranslational modifications of DNA repair proteins have been linked to their function. However, it is not clear if posttranslational acetylation affects subcellular localization of these enzymes. Here, we show that the human DNA glycosylase NEIL1, which is involved in repair

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