D9625
2′-Deoxyguanosine 5′-monophosphate
≥97%
Synonym(s):
5′-Deoxyguanylic acid, dGMP
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About This Item
Empirical Formula (Hill Notation):
C10H14N5O7P
CAS Number:
Molecular Weight:
347.22
EC Number:
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
Recommended Products
Assay
≥97%
form
solid
storage temp.
−20°C
SMILES string
NC1=NC(=O)c2ncn(C3CC(O)C(COP(O)(O)=O)O3)c2N1
InChI
1S/C10H14N5O7P/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17)
InChI key
LTFMZDNNPPEQNG-UHFFFAOYSA-N
comparable product
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Jean L Whittingham et al.
The Biochemical journal, 428(3), 499-509 (2010-04-01)
Plasmodium falciparum is the causative agent of malaria, a disease where new drug targets are required due to increasing resistance to current anti-malarials. TMPK (thymidylate kinase) is a good candidate as it is essential for the synthesis of dTTP, a
Takahito Ohshiro et al.
Micromachines, 11(11) (2020-11-05)
We utilized electrophoresis to control the fluidity of sample biomolecules in sample aqueous solutions inside the nanochannel for single-molecule detection by using a nanochannel-integrated nanogap electrode, which is composed of a nano-gap sensing electrode, nanochannel, and tapered focusing channel. In
Paolo Mariani et al.
The journal of physical chemistry. B, 113(22), 7934-7944 (2009-05-14)
To solve details of the self-assembling process of guanosine in diluted aqueous solution and to derive a thermodynamical model for quadruplex formation, the structural behavior of deoxyguanosine 5'-monophosphate has been analyzed by in-solution small angle X-ray scattering. The experiments have
Aya Kato et al.
Parasitology international, 61(3), 501-503 (2012-03-20)
During the course of our research into new anti-malaria drugs, Plasmodium falciparum thymidylate kinase (PfTMK) has emerged as an important drug target because of its unique substrate specificity. Compared with human thymidylate kinase (HsTMK), PfTMK shows broader substrate specificity, which
Constance Auvynet et al.
Biochemical and biophysical research communications, 388(1), 6-11 (2009-07-28)
Vaccinia virus thymidylate kinase, although similar in sequence to human TMP kinase, has broader substrate specificity and phosphorylates (E)-5-(2-bromovinyl)-dUMP and dGMP. Modified guanines such as glyoxal-dG, 8-oxo-dG, O(6)-methyl-dG, N(2)-ethyl-dG and N(7)-methyl-dG were found present in cancer cell DNA. Alkylated and
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