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Key Documents

D8938

Sigma-Aldrich

KIMBLE Dounce tissue grinder set

2 mL complete

Synonym(s):

885300-0002, Dounce, Dounce Homogenizer, Glass Tissue Grinder, KIMBLE Tissue Grinder, KONTES, Pestles, Tissue Grinder, Tubes

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About This Item

UNSPSC Code:
41121800
NACRES:
NB.22

material

glass

feature

autoclavable

manufacturer/tradename

Kimble® 885300-0002

pestle A clearance

0.0030-0.0050 in.

pestle B clearance

0.0005-0.0025 in.

working volume × L

2 mL × 60 mm

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General description

Designed primarily for cellular work where the nucleus remains intact after homogenization. All-glass construction. Two pestles are supplied with each complete set. Large clearance pestle is used for the initial sample reduction. Small clearance pestle is used to form the final homogenate.

Features and Benefits

• Manufactured from borosilicate glass 3.3• Designed primarily for cellular work where the nucleus remains intact after homogenization.• All-glass construction• Two pestles are supplied with each complete unit• Large clearance pestle is used for the initial sample reduction• Small clearance pestle is used to form the final homogenate• Replacement components are available and completely interchangeable

Legal Information

KIMBLE is a registered trademark of DWK Life Sciences

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Naomi Habib et al.
Nature neuroscience, 23(6), 701-706 (2020-04-29)
The role of non-neuronal cells in Alzheimer's disease progression has not been fully elucidated. Using single-nucleus RNA sequencing, we identified a population of disease-associated astrocytes in an Alzheimer's disease mouse model. These disease-associated astrocytes appeared at early disease stages and
Fang-Yuan Hu et al.
Frontiers in bioengineering and biotechnology, 8, 564057-564057 (2020-10-20)
Retina is a crucial tissue for capturing and processing light stimulus. It is critical to describe the characteristics of retina at the single-cell level for understanding its biological functions. A variety of abnormalities in terms of morphology and function are
Naomi Habib et al.
Nature methods, 14(10), 955-958 (2017-08-29)
Single-nucleus RNA sequencing (sNuc-seq) profiles RNA from tissues that are preserved or cannot be dissociated, but it does not provide high throughput. Here, we develop DroNc-seq: massively parallel sNuc-seq with droplet technology. We profile 39,111 nuclei from mouse and human
Sripriya Ravindra Kumar et al.
Nature methods, 17(5), 541-550 (2020-04-22)
Recombinant adeno-associated viruses (rAAVs) are efficient gene delivery vectors via intravenous delivery; however, natural serotypes display a finite set of tropisms. To expand their utility, we evolved AAV capsids to efficiently transduce specific cell types in adult mouse brains. Building
Jonathan M Levy et al.
Nature biomedical engineering, 4(1), 97-110 (2020-01-16)
The success of base editors for the study and treatment of genetic diseases depends on the ability to deliver them in vivo to the relevant cell types. Delivery via adeno-associated viruses (AAVs) is limited by AAV packaging capacity, which precludes

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