C7602

L-Cystine

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

• Synonym(s): (R,R)-3,3′-Dithiobis(2-aminopropionicacid)
• Linear Formula: [-SCH₂CH(NH₂)CO₂H]₂
• CAS Number: 56-89-3
• Molecular Weight: 240.30
• Beilstein: 1728094
• EC Number: 200-296-3
• MDL number: MFCD00064228
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24892973
• NACRES: NA.26

Properties

• product name: L-Cystine, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%
• biological source: non-animal source
• Agency: meets EP testing specifications
• product line: BioXtra
• Assay: 98.5-101.0%
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white to off-white
• mp: >240 °C (dec.) (lit.)
• solubility: 1 M HCl: 100 mg/mL
• application(s): peptide synthesis
• SMILES string: N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O
• InChI: 1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
• InChI key: LEVWYRKDKASIDU-IMJSIDKUSA-N

Description

Application

L-Cystine has been used as a supplement in astroglial-conditioned media to culture cerebral astroglia. It has been used in several techniques, such as HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry (UHPLC-MS/MS), to differentiate BMAA (β-N-methylamino-L-alanine), the cyanobacterial neurotoxin, from other diamino acids.
L-Cystine has been used as a supplement in oocyte culture media to improve oocyte maturation and parthenogenesis of embryonic development.

Biochem/physiol Actions

Cystinuria is characterized with renal transport and excretion of L-Cystine. Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cystine is necessary for oxygen production and LDL (low density lipoprotein) modification by arterial smooth muscle cells.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves