C3637

Z-L-Lys-ONp hydrochloride

≥98% (HPLC)

• Synonym(s): N²-[(phenylmethoxy)carbonyl]-L-lysine 4-nitrophenyl ester hydrochloride (1:1)
• Empirical Formula (Hill Notation): C₂₀H₂₃N₃O₆ · HCl
• CAS Number: 2179-15-9
• Molecular Weight: 437.87
• EC Number: 218-546-5
• MDL number: MFCD00039055
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24892631
• NACRES: NA.26

Properties

• product name: Z-L-Lys-ONp hydrochloride,
• Assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: methanol: 50 mg/mL, clear, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: Cl[H].NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Oc2ccc(cc2)[N+]([O-])=O
• InChI: 1S/C20H23N3O6.ClH/c21-13-5-4-8-18(22-20(25)28-14-15-6-2-1-3-7-15)19(24)29-17-11-9-16(10-12-17)23(26)27;/h1-3,6-7,9-12,18H,4-5,8,13-14,21H2,(H,22,25);1H/t18-;/m0./s1
• InChI key: JFZLPXVXTZKFDV-FERBBOLQSA-N

Description

Application

Z-L-Lys-ONp hydrochloride has been used as a substrate for trypsin to monitor hydrolysis reaction using mass spectroscopy studies.

Biochem/physiol Actions

N-α-carbobenzoxy-L-lysine-p-nitrophenyl ester (Z-L-Lys-ONp) is a para-nitrophenol ester of N-CBZ-L-lysine. Z-L-Lys-ONp and other N-CBZ-amino acid p-nitrophenol esters are chromogenic substrates used for the differentiation and characterization of proteases and endopeptidases. It acts as a substrate for bromelain.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves