C1108
Anti-Cannabinoid Receptor 1 antibody produced in rabbit
affinity isolated antibody, buffered aqueous glycerol solution
Synonym(s):
Anti-CANN6, Anti-CB-R, Anti-CB1, Anti-CB1A, Anti-CB1K5, Anti-CB1R, Anti-CNR
Sign Into View Organizational & Contract Pricing
Select a Size
0.1 ML
CHF 556.00
CHF 556.00
Estimated to ship on16 April 2025
All Photos(1)
Select a Size
Change View
0.1 ML
CHF 556.00
About This Item
CHF 556.00
Estimated to ship on16 April 2025
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen ~52 kDa
species reactivity
rat, human
concentration
1 mg/mL
technique(s)
immunocytochemistry: suitable
western blot: suitable
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CNR1(1268)
rat ... Cnr1(25248)
Looking for similar products? Visit Product Comparison Guide
Immunogen
fusion protein containing amino acids 1-99 of the human CB1 receptor.
Application
Anti-Cannabinoid Receptor 1 antibody produced in rabbit is suitable for western blotting at a working dilution of 1:250 and for immunocytochemistry at a working dilution of 1:1000.
Biochem/physiol Actions
Cannabinoids exert their well-known physiological effects through two G-protein coupled receptors, CB1 and CB2. The cannabinoid receptor type 1 (CB1) is widely distributed in mammalian tissues, with the highest concentrations found in brain neurons while CB2 receptor function primarily in the peripheral immune system, found in spleen and may be present in the central nervous system, including the retina. The cannabinoid receptor type 1 are involved in modulation of adenylate cyclase and ion channels. It is also involved in the modulation of nociception, movement, learning and memory, emotion and many other neuronal processes. It also plays an essential role in drug addiction. CB1 receptor blockade may be useful for treatment of angiotensin II-dependent hypertension and associated metabolic syndrome.
Physical form
Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin, 50% glycerol, and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Hajar Miranzadeh Mahabadi et al.
Molecular brain, 14(1), 89-89 (2021-06-09)
The type 1 and type 2 cannabinoid receptors (CB1 and CB2 receptors) are class A G protein-coupled receptors (GPCRs) that are activated by endogenous lipids called endocannabinoids to modulate neuronal excitability and synaptic transmission in neurons throughout the central nervous
Thangesweran Ayakannu et al.
Frontiers in oncology, 9, 430-430 (2019-06-28)
Objective: To identify new biochemical markers for endometrial cancer (EC). Recent evidence suggests that members of the endocannabinoid system (N-acylethanolamines) that bind to and activate receptors that are dysregulated in EC are involved in this tumour's biology. These observations suggest
R G Pertwee
Current medicinal chemistry, 6(8), 635-664 (1999-09-02)
Mammalian tissues contain at least two types of cannabinoid receptor, CB1 and CB2, both coupled to G proteins. CB1 receptors are expressed mainly by neurones of the central and peripheral nervous system whereas CB2 receptors occur in certain non-neuronal tissues
Li Jing et al.
Drug and alcohol dependence, 143, 251-256 (2014-08-30)
Cannabinoid CB1 receptors play an essential role in drug addiction. Given the side effect profiles of orthosteric CB1 antagonism, new strategies have been attempted to modulate this target, such as CB1 receptor allosteric modulation. However, the effect of CB1 allosteric
C C Felder et al.
Annual review of pharmacology and toxicology, 38, 179-200 (1998-05-23)
Marijuana has been in use for over 4000 years as a therapeutic and as a recreational drug. Within the past decade, two cannabinoid receptor types have been identified, their signal transduction characterized, and an endogenous lipid agonist isolated from mammalian
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
