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A5758

Sigma-Aldrich

Antifoam Y-30 Emulsion

aqueous-silicone emulsion

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About This Item

UNSPSC Code:
12161900

Quality Level

200

form

emulsion

contains

emulsifier

General description

Antifoam Y-30 Emulsion is an aqueous emulsion containing 30% active silicon. It contains non-ionic emulsifiers different from those in Antifoam Emulsions B and C. It is designed to control foam in aqueous systems.
Antifoam is also known as defoamer. It is a chemical additive that reduces and hinders the formation of foam in industrial process liquids. It is used to prevent formation of foam or is added to break foam that is already formed.

Application

Antifoam Y-30 Emulsion is used for the following applications:
  • Chemostat cultivation.[1]
  • Cultivation conditions, such as Fed-batch fermentation.[2][3]
  • Bacterial strains and growth conditions (used in all aerosol experiments).[4]

Other Notes

A 30% aqueous emulsion of Antifoam A concentrate.

Linkage

More easily dispersed in aqueous systems than Antifoam A concentrate.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCJ9418
MKCF1896
MKCC6091
MKBZ1756V
MKBX0199V

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Adrien Pagnier et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(1), 104-109 (2015-12-25)
The synthesis and assembly of the active site [FeFe] unit of [FeFe]-hydrogenases require at least three maturases. The radical S-adenosyl-l-methionine HydG, the best characterized of these proteins, is responsible for the synthesis of the hydrogenase CO and CN(-) ligands from
Modeling of growth and energy metabolism of Pichia pastoris producing a fusion protein.
M. Jahic, J.C. Rotticci-Mulder, M. Martinelle, K. Hult, S-O. Enfors
Bioprocess and Biosystems Engineering, 24, 385-393 (2002)
Divey Saini et al.
Tuberculosis (Edinburgh, Scotland), 92(2), 160-165 (2011-12-27)
A murine low dose (LD) aerosol model is commonly used to test tuberculosis vaccines. Doses of 50-400 CFU (24h lung CFU) infect 100% of exposed mice. The LD model measures progression from infection to disease based on organ CFU at
Mehmedalija Jahic et al.
Microbial cell factories, 2(1), 6-6 (2003-07-23)
BACKGROUND: A temperature limited fed-batch (TLFB) technique is described and used for Pichia pastoris Mut+ strain cultures and compared with the traditional methanol limited fed-batch (MLFB) technique. A recombinant fusion protein composed of a cellulose-binding module (CBM) from Neocallimastix patriciarum
Sarah J Routledge et al.
Methods in molecular biology (Clifton, N.J.), 866, 87-97 (2012-03-29)
Pichia pastoris is a widely used host for recombinant protein production. The foaming associated with culturing it on a large scale is commonly prevented by the addition of chemical antifoaming agents or "antifoams." Unexpectedly, the addition of a range of
View All Related Papers

Questions

1–9 of 9 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Are Antifoam A (product number 10794) and Antifoam Y-30 (product number A5758) the same product? Can I use Antifoam Y-30 (product number A5758) as a replacement for Antifoam A (product number 10794)?

    1 answer

    1. The A5758, Antifoam Y-30, is a 30% solution containing non-ionic emulsifiers. It is prepared from an Antifoam A product that does not contain emulsifiers. The 10794, Antifoam A, is a deleted product, but was also a 30% solution containing emulsifiers. These products are from different brands, but functionally are identical and may be used interchangeably.

      Please view the link below for the product information sheet for the offered Antifoam products:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/136/342/a5758pis.pdf

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  4. How can Product No. A5758, Antifoam Y-30 Emulsion be used?

    1 answer

    1. This antifoam can be diluted with water. It is effective at low concentrations (1-100 ppm is the usual range to use). Trials can start at 50 ppm (active silicone), and amounts may be reduced to where the level of foam control is desired. The product should be agitated before use.

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  5. What is Antifoam Y-30 emulsion?

    1 answer

    1. Antifoam Y-30 emulsion,a Dow-Corning product, is a 30% active silicone emulsion, whose usage is intended for controlling foam in aqueous systems. The composition of the antifoam is considered proprietary by the manufacturer.  However, the emulsifier type is described as nonionic.

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  6. What is the difference between product A5758, Antifoam Y-30 emulsion and product A6457?

    1 answer

    1. Product A6457, a molecular biology reagent, has been function-tested by Sigma for use in bacterial fermentation. Product A5758 has not been tested in this application by Sigma.

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  7. Has there been a name change for Antifoam Y-30 Emulsion, Product A5758?

    1 answer

    1. Yes. The product was formerly listed under the name "Antifoam A Emulsion".  Although there has been a name change, there is no change in the composition of the antifoam. It is the same product.

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  8. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  9. Can Antifoam Y-30 Emulsion, Product A5758, be autoclaved?

    1 answer

    1. Dow Corning® does not recommend that the emulsion be autoclaved since autoclaving can adversely affect the product.

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