Firoin from Rhodothermus marinus, an extremolyte, may be used in the development of potential new formulations to enhance the stability of retroviral and adenoviral vectors.
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Bottomless glass bottle. Contents are inside inserted fused cone.
Applied microbiology and biotechnology, 72(4), 623-634 (2006-09-08)
Extremophilic microorganisms have adopted a variety of ingenious strategies for survival under high or low temperature, extreme pressure, and drastic salt concentrations. A novel application area for extremophiles is the use of "extremolytes," organic osmolytes from extremophilic microorganisms, to protect
In the past decade there has been an increase in the application of viral vectors in the laboratory and clinical trials of human gene therapy, retroviral and adenoviral vectors among the most used. However, the limited stability of these vectors
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