Y0000529
Sulbactam sodium
European Pharmacopoeia (EP) Reference Standard
Synonym(s):
Sulbactam sodium salt
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About This Item
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grade
pharmaceutical primary standard
API family
sulbactam
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
[Na+].[S]1(=O)(=O)[C@H]2N([C@H](C1(C)C)C(=O)[O-])C(=O)C2
InChI
1S/C8H11NO5S.Na/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14;/h5-6H,3H2,1-2H3,(H,11,12);/q;+1/p-1/t5-,6+;/m1./s1
InChI key
NKZMPZCWBSWAOX-IBTYICNHSA-M
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Sulbactam sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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Y-T Lee et al.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 32(9), 1211-1220 (2013-04-05)
Tigecycline (TG) has been shown to be active in vitro against Acinetobacter baumannii, although data on the clinical efficacy of TG alone or in combination for the treatment of infections due to multidrug-resistant A. baumannii (MDRAB) remain limited. The purpose
Alaa A Hassan et al.
Archiv der Pharmazie, 346(7), 562-570 (2013-06-19)
(E)-4-Aryl-2-[2-(1-substituted ethylidene)hydrazinyl]thiazoles and (Z)-3-substituted-4-aryl-2-[(E)-(1-phenylethylidene)hydrazono]-2,3-dihydrothiazoles were synthesized by the reaction of (substituted ethylidene)hydrazinecarbothioamides with ω-bromoacetophenones. The characterization of this new class of compounds was performed using different spectroscopic tools. The structure of (Z)-3-benzyl-4-(4-bromophenyl)-2-[(E)-(1-phenylethylidene)hydrazono]-2,3-dihydrothiazole 6e was unambiguously confirmed by single-crystal X-ray crystallography.
Rui Li et al.
Journal of molecular modeling, 19(6), 2519-2524 (2013-03-05)
The imine intermediates of tazobactam and sulbactam bound to SHV-1 β-lactamase were investigated by molecular dynamics (MD) simulation respectively. Hydrogen bond networks around active site were found different between tazobactam and sulbactam acyl-enzymes. In tazobactam imine intermediate, it was observed
Seyedali Seyedmajidi et al.
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 14(1), 1-5 (2013-04-30)
Selection of the best drug regimens for eradication of Helicobacter pylori infection especially in patients at risk of peptic ulcer relapses and the development of complications is challenging. This study assessed and compared the efficacy of the two common PPI
Mengtao Zhou et al.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 13(3), 212-215 (2013-05-31)
Our aim was to investigate the efficiency of continuous regional intra-arterial infusion (CRAI) with antisecretory agents and antibiotics in the treatment of infected pancreatic necrosis. CRAI was used as a new clinical technique to treat acute pancreatitis patients during a
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