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F6270

Supelco

Fipexide hydrochloride

analytical standard

Synonym(s):

1-(2-[4-Chlorophenoxy]acetyl)-4-(3,4-methylenedioxybenzyl)piperazine

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About This Item

Empirical Formula (Hill Notation):
C20H21ClN2O4 · HCl
CAS Number:
34161-24-5
Molecular Weight:
425.31
EC Number:
251-857-4
MDL number:
MFCD00133323
UNSPSC Code:
41116107
PubChem Substance ID:
329799752
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.Clc1ccc(OCC(=O)N2CCN(CC2)Cc3ccc4OCOc4c3)cc1

InChI

1S/C20H21ClN2O4.ClH/c21-16-2-4-17(5-3-16)25-13-20(24)23-9-7-22(8-10-23)12-15-1-6-18-19(11-15)27-14-26-18;/h1-6,11H,7-10,12-14H2;1H

InChI key

MVOWQBJZZKOQNU-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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André Leblanc et al.
Rapid communications in mass spectrometry : RCM, 24(9), 1241-1250 (2010-04-15)
Drug bioactivation leading to the formation of reactive species capable of covalent binding to proteins represents an important cause of drug-induced toxicity. Reactive metabolite detection using in vitro microsomal incubations is a crucial step in assessing potential toxicity of pharmaceutical
L Lucchi et al.
Brain research, 398(1), 212-214 (1986-11-19)
The release of Met-enkephalin immunoreactive material (ME-IR) from rat striatal slices is affected by exposure to amphetamine and fipexide (chloro-4-phenoxy)-2-acetyl-1-(methylene-dioxy 3, 4-benzyl-4-piperazine) a psychostimulant drug with mild dopaminomimetic activity. Both amphetamine and fipexide inhibited in vitro the release of ME-IR.
R Bompani et al.
Current medical research and opinion, 10(2), 99-106 (1986-01-01)
Forty geriatric in-patients with severe cognition disorders were randomly allocated to treatment with either 600 mg fipexide daily or placebo over a period of 3 weeks. Before and after treatment, the symptoms of cognitive performance (disorders of memory and attention
[Fever after taking fipexide hydrochloride].
C Guy et al.
Presse medicale (Paris, France : 1983), 18(21), 1076-1076 (1989-05-27)
Xiaochun Zhu et al.
Analytical chemistry, 83(24), 9516-9523 (2011-11-15)
A selective and sensitive approach, called extraction of product ion (XoPI) method, was developed for the detection of l-glutathione (GSH)-trapped reactive metabolites employing an Orbitrap high resolution mass spectrometer. Fragmentation of GSH conjugates in the negative ion mode leads to
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