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09779

Sigma-Aldrich

Fmoc-12-Ado-OH

≥98.0% (TLC)

Synonym(s):

12-(Fmoc-amino)dodecanoic acid

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About This Item

Empirical Formula (Hill Notation):
C27H35NO4
CAS Number:
128917-74-8
Molecular Weight:
437.57
Beilstein:
9593537
MDL number:
MFCD00235888
UNSPSC Code:
12352209
PubChem Substance ID:
329748826
NACRES:
NA.26

Quality Level

100

Assay

≥98.0% (TLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

color

white

mp

114-118 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)CCCCCCCCCCCNC(=O)OCC1c2ccccc2-c3ccccc13

InChI

1S/C27H35NO4/c29-26(30)18-8-6-4-2-1-3-5-7-13-19-28-27(31)32-20-25-23-16-11-9-14-21(23)22-15-10-12-17-24(22)25/h9-12,14-17,25H,1-8,13,18-20H2,(H,28,31)(H,29,30)

InChI key

HVGIKYAQSSNFCH-UHFFFAOYSA-N

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCB7406
BCBQ4746V
BCBQ3961V
BCBP2244V
BCBD4144V

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Christos Kontos et al.
Nature communications, 11(1), 5981-5981 (2020-11-27)
Targeting a specific chemokine/receptor axis in atherosclerosis remains challenging. Soluble receptor-based strategies are not established for chemokine receptors due to their discontinuous architecture. Macrophage migration-inhibitory factor (MIF) is an atypical chemokine that promotes atherosclerosis through CXC-motif chemokine receptor-4 (CXCR4). However
Jing Han et al.
Molecular pharmaceutics, 15(7), 2840-2856 (2018-05-26)
GLP-1 analogs suffer from the main disadvantage of a short in vivo half-life. Lithocholic acid (LCA), one of the four main bile acids in the human body, possesses a high albumin binding rate. We therefore envisioned that a LCA-based peptide

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