8.17059

Triethyl citrate

EMPROVE^® ESSENTIAL, Ph. Eur., ChP, JPE, NF

• Synonym(s): Triethyl citrate, Citric acid triethyl ester
• Linear Formula: HOC(COOC₂H₅)(CH₂COOC₂H₅)₂
• CAS Number: 77-93-0
• Molecular Weight: 276.28
• MDL number: MFCD00009201
• UNSPSC Code: 12352108
• EC Index Number: 201-070-7

Properties

• Agency: ChP; JPE; NF; Ph. Eur.
• Quality Level: 500
• vapor pressure: 0.0025 hPa ( 25 °C)
• description: EMPROVE^® ESSENTIAL Ph Eur,JPE,NF
• product line: EMPROVE^® ESSENTIAL
• form: viscous liquid
• potency: >5000 mg/kg LD₅₀, skin (Rabbit)
• bp: 294 °C/1013 hPa
• mp: -55 °C
• transition temp: flash point 150 °C
• density: 1.135 g/cm³ at 25 °C
• application(s): liquid formulation; pharmaceutical; solid formulation
• shipped in: ambient
• storage temp.: 15-25°C
• SMILES string: O(CC)C(=O)C(O)(CC(=O)OCC)CC(=O)OCC
• InChI: 1S/C12H20O7/c1-4-17-9(13)7-12(16,11(15)19-6-3)8-10(14)18-5-2/h16H,4-8H2,1-3H3
• InChI key: DOOTYTYQINUNNV-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Triethylcitrate is typically used as pH adjuster, antioxidant, buffer agent or plasticizer in pharmaceutical coatings.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 311.0 °F - closed cup
• Flash Point(C): 155 °C - closed cup