C-090

Citalopram-D₆ hydrobromide solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₀D₆H₁₅FN₂O · HBr
• CAS Number: 1190003-26-9
• Molecular Weight: 411.34
• EC Number: 200-659-6
• MDL number: MFCD27966798
• UNSPSC Code: 41116107
• PubChem Substance ID: 329774824
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol (as free base)
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: FC(C=C1)=CC=C1C2(CCCN(C([2H])([2H])[2H])C([2H])([2H])[2H])C3=CC=C(C#N)C=C3CO2.Br
• InChI: 1S/C20H21FN2O.BrH/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;/h4-9,12H,3,10-11,14H2,1-2H3;1H/i1D3,2D3;
• InChI key: WIHMBLDNRMIGDW-TXHXQZCNSA-N

Description

General description

Citalopram is an antidepressant sold under the trade names Celexa^® and Cipramil for the treatment of major depression. Citalopram is a selective serotonin reuptake inhibitor, a class of drugs that also includes fluoxetine, paroxetine, and sertraline. This internal standard is suitable for quantitation of citalopram levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or isotope dilution methods.

Application

• Advancements in analytical methods for psychoactive drugs: A fast UPLC-MS/MS screening method was developed for detecting psychoactive drugs and metabolites in whole blood, incorporating Citalopram-D₆ hydrobromide as an internal standard to enhance precision in neurochemical analysis, especially in post-mortem cases. This method underscores the critical role of high-purity deuterated derivatives in biochemical research (Barone et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Celexa is a registered trademark of H. Lundbeck A/S

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup