Skip to Content
Merck
All Photos(1)

Documents

870703P

Avanti

03:0 Coenzyme A

Avanti Research™ - A Croda Brand 870703P, powder

Synonym(s):

propanoyl Coenzyme A (sodium salt)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C24H37N7Na3O17P3S
CAS Number:
317-66-8
Molecular Weight:
889.54
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (870703P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870703P

application(s)

lipidomics

lipid type

coenzymes

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@@](C(NCCC(NCCSC(CC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[Na+].[Na+].[Na+]

InChI

1S/C24H40N7O17P3S/c1-4-15(33)52-8-7-26-14(32)5-6-27-22(36)19(35)24(2,3)10-45-51(42,43)48-50(40,41)44-9-13-18(47-49(37,38)39)17(34)23(46-13)31-12-30-16-20(25)28-11-29-21(16)31/h11-13,17-19,23,34-35H,4-10H2,1-3H3,(H,26,32)(H,27,36)(H,40,41)(H,42,43)(H2,25,28,29)(H2,37,38,39)

InChI key

QAQREVBBADEHPA-UHFFFAOYSA-N

General description

03:0 Coenzyme A, also known as propanoyl coenzyme A, is a coenzyme A derivative of propionic acid. It is a catabolite of the amino acids isoleucine, valine, methionine, and threonine.

Biochem/physiol Actions

03:0 Coenzyme A acts as a substrate for methyl citrate synthase (PrpC), an important enzyme involved in tricarboxylic acid (TCA) cycle. It is a metabolic intermediate in the 1,2-propanediol and propionate degradation pathway of Salmonella enterica serovar Typhimurium LT2. Accumulation of propanoyl coenzyme A due to the deficiency of propionyl-coenzyme A (CoA) carboxylase causes propionic acidemia (PA).

Packaging

5 mL Amber Glass Screw Cap Vial (870703P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jessica Ramsay et al.
Annals of translational medicine, 6(24), 472-472 (2019-02-12)
Organic acids (OAs) are intermediary products of several amino acid catabolism or degradation via multiple biochemical pathways for energy production. Vitamins or co-factors are often quintessential elements in such degradation pathways and OA metabolism. OAs that result from enzyme defects
Chapter 5.2-Vitamins and minerals
Human physiology, biochemistry and basic medicine, 165-175 (2016)
Sergio Palacios et al.
Journal of bacteriology, 185(9), 2802-2810 (2003-04-18)
The studies reported here identify propionyl coenzyme A (propionyl-CoA) as the common intermediate in the 1,2-propanediol and propionate catabolic pathways of Salmonella enterica serovar Typhimurium LT2. Growth on 1,2-propanediol as a carbon and energy source led to the formation and

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service