QBD10722
Hydroxy-dPEG®24-t-butyl ester
>90% (HPLC)
Synonym(s):
HO-PEG24-CO-Otbu, HO-PEG24-TBE, Hydroxy-PEG-t-butyl ester, Hydroxy-PEG24-t-butyl-ester, PEG1000-t-butyl ester
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About This Item
Empirical Formula (Hill Notation):
C55H110O27
Molecular Weight:
1203.45
MDL number:
UNSPSC Code:
12352108
NACRES:
NA.22
Recommended Products
Assay
>90% (HPLC)
form
solid or viscous liquid
reaction suitability
reaction type: Pegylations
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
Features and Benefits
Hydroxy-dPEG24-t-butyl ester is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain, comparable to a polymeric PEG1000. The single molecular weight, discrete-length PEG (dPEG) chain is 86 atoms (88.5 Å) long. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. The tert-butyl ester deprotects with trifluoroacetic acid (TFA), exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.
Legal Information
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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