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ALD00592

Sigma-Aldrich

N-Boc-N′-TFA-pyrazole-1-carboxamidine

95%

Synonym(s):

N-Boc,N′-trifluoroacetyl-guanylpyrazole, tert-Butyl-((1H-pyrazol-1-yl)(2,2,2-trifluoroacetamido)methylene)carbamate, TurboGuan

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About This Item

Empirical Formula (Hill Notation):
C11H13F3N4O3
Molecular Weight:
306.24
UNSPSC Code:
12352101
NACRES:
NA.22

Quality Level

Assay

95%

form

powder or crystals

mp

120-125 °C

application(s)

peptide synthesis

storage temp.

−20°C

Application

Powerful guanidinylation reagent from the Baran Lab developed for the installation of monoprotected boc-guanidine on primary and secondary amines, particularly electron-deficient and hindered amines.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Related Content

The Baran Group works with Sigma-Aldrich in providing a portfolio of zinc-based reagents promoting difluoromethylation, trifluoromethylation, trifluoroethylation and isopropylation of aryl and heteroaryl motifs. Baran’s lab has also helped introduce a portable desaturase (Tz0Cl), which promotes the installation of alcohol and amine groups and leaves behind a highly useful tosyl group for further transformations.

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